Eur J Prev Cardiol:中国科学家团队发现,怀孕生娃会增加女性的心脏病风险

2018-12-28 符苏 生物探索

根据一篇发表在《European Society of Cardiology》期刊上的最新文章揭示,与从未生过孩子的女性相比,怀孕生过小孩的女性发生心脏病、中风的风险相对高出14%。

怀孕生娃对于一个女人的影响究竟有多大?

皮肤会松弛,长斑、妊娠纹……

睡眠质量变差,腰疼、黑眼圈……

免疫力下降,孕吐、脱发……

事实上,怀孕对于女性的影响远远不止这些:

根据一篇发表在《European Society of Cardiology》期刊上的最新文章揭示,与从未生过孩子的女性相比,怀孕生过小孩的女性发生心脏病、中风的风险相对高出14%。

这一篇论文由华中科技大学同济医学院公共卫生学院的Dongming Wang团队完成。

01.生孩子增加心脏病风险?

怀孕期间,心脏负担会加重,以满足母亲和胎儿的需要。但是,怀孕对于后续心脏病发生的影响一直存在争议。

现在,Dongming Wang团队统计了来自全球各地的数据,并进行了荟萃分析,共囊括了3,089,929名女性,其中有150,512名女性在随访期间(6-52年)确诊患有心脏病或中风。

总体分析发现,怀孕生娃与血管疾病风险之间存在显着的相关性——妊娠、分娩过的女性患心脏病或中风的几率比从未生过孩子的女性高14%。

02.怀孕次数越多,风险越大

值得注意的是,分析数据揭示,伴随着怀孕次数的增加,血管疾病风险也会累加。有证据表明,两者存在“J型”关系。

无论体重指数、糖尿病高血压、吸烟和收入水平等因素,女性每次生孩子都会导致心血管疾病发病率增加4%。具体而言,每分娩一次会增加5%的冠心病风险、3%的中风风险。


图片来源:European Society of Cardiology

03.背后的原因

为什么会有这份关联?Dongming Wang表示,这背后的机制很复杂。

他认为,怀孕可能导致身体发炎,脂肪组织堆积在腹部、血液和动脉周围。这些变化会对心血管系统产生永久性影响,导致心脏病、中风的风险增加。

“女性应该知道生孩子可能会增加未来发生心脏病、中风的概率。而且,怀孕次数越多,相关风险可能越大。” Dongming Wang解释道,“好消息是,女性可以做很多事情来预防心血管疾病。”

毕竟,怀孕是摆脱不良生活习惯的好时机,包括戒烟、定期运动、吃健康食物、控制体重、减少腹部脂肪,并注意饮食中的脂肪含量,以保持血脂健康。

这篇论文在摘要中强调,由于纳入分析的研究数量有限,所以仍然需要进一步的研究来证实怀孕生娃与心血管疾病风险之间的关联。

原始出处:Wenzhen Li, Wenyu Ruan, Zuxun Lu, et al. Parity and risk of maternal cardiovascular disease: A dose–response meta-analysis of cohort studies. Eur J Prev Cardiol. December 19, 2018

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    2018-12-31 医者仁心5538

    学习了

    0

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    2018-12-28 topnew

    觉得怀孕生娃的风险远不及养娃的风险高,看娃写作业,发生心梗的病例不止一个两个

    0

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