Pharmacological Research: 连花清瘟体外试验显示抗新冠病毒抗炎作用

2020-03-24 科学网 科学网

中国工程院院士钟南山团队最新研究认为,连花清瘟在体外试验中显示出抗新冠病毒的作用。

中国工程院院士钟南山团队最新研究认为,连花清瘟在体外试验中显示出抗新冠病毒的作用。

相关论文题为《连花清瘟对新型冠状病毒具有抗病毒、抗炎作用》“Lianhuaqingwen exerts anti-viral and anti-inflammatory activity against novel coronavirus (SARS-CoV-2)”,已被《药理学研究》期刊(Pharmacological Research)接收。

论文作者包括广州医科大学呼吸疾病国家重点实验室主任钟南山、研究员杨子峰等。

论文提到,作为一种中药方剂,连花清瘟对一系列流感病毒具有广谱抗病毒作用和免疫调节作用。

研究人员使用CPE和空斑减数实验,在Vero E6细胞中评估了连花清瘟对SARS-CoV-2的抗病毒活性。

在透射电子显微镜下可见连花清瘟对病毒体形态的影响。

通过实时定量PCR测定法测量Huh-7细胞中SARS-CoV-2感染后促炎细胞因子的表达水平。

试验结果表明,连花清瘟在mRNA水平上显著抑制SARS-CoV-2在Vero E6细胞中的复制,并显著降低促炎细胞因子(TNF-α,IL-6,CCL-2 / MCP-1和CXCL-10 / IP-10)的产生。此外,连花清瘟处理导致细胞中病毒粒子的颗粒形态异常。

论文总结道,连花清瘟显著抑制SARS-COV-2复制,影响病毒形态并在体外发挥抗炎活性。这表明连花清瘟可以抵抗病毒攻击,有望成为控制COVID-19疾病的新策略。

原始出处:
Li RunFeng,et al. Lianhuaqingwen exerts anti-viral and anti-inflammatory activity against novel coronavirus (SARS-CoV-2).Pharmacological Research. 20 Martch, 2020

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    2020-11-25 lovetcm

    #连花清瘟胶囊#,这是#钟南山#院士做的研究成果,说实话,这个研究水平是相当低的,而且仅仅是#体外研究#,与临床研究完全不一样,也根本无法说明连花清瘟胶囊能够对抗#新冠肺炎#。但是,也不能苛求,就中药企业而言,这家公司已经是最好的了。再怎么说,人家还拿出一点证据,至少比#双黄连#强上很多倍

    0

  4. 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    2020-12-31 yb6560
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createdBy=f634250, createdName=chentianping, createdTime=Fri Nov 27 16:54:20 CST 2020, time=2020-11-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=902129, encodeId=d34a90212967, content=<a href='/topic/show?id=4ea394569ed' target=_blank style='color:#2F92EE;'>#连花清瘟胶囊#</a>,这是<a href='/topic/show?id=6cce9642674' target=_blank style='color:#2F92EE;'>#钟南山#</a>院士做的研究成果,说实话,这个研究水平是相当低的,而且仅仅是<a href='/topic/show?id=568010405429' target=_blank style='color:#2F92EE;'>#体外研究#</a>,与临床研究完全不一样,也根本无法说明连花清瘟胶囊能够对抗<a href='/topic/show?id=46ce580e865' target=_blank style='color:#2F92EE;'>#新冠肺炎#</a>。但是,也不能苛求,就中药企业而言,这家公司已经是最好的了。再怎么说,人家还拿出一点证据,至少比<a href='/topic/show?id=a7533e66013' target=_blank style='color:#2F92EE;'>#双黄连#</a>强上很多倍, beContent=null, objectType=article, channel=null, level=null, likeNumber=168, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94569, encryptionId=4ea394569ed, topicName=连花清瘟胶囊), TopicDto(id=96426, encryptionId=6cce9642674, 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  8. 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createdBy=f634250, createdName=chentianping, createdTime=Fri Nov 27 16:54:20 CST 2020, time=2020-11-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=902129, encodeId=d34a90212967, content=<a href='/topic/show?id=4ea394569ed' target=_blank style='color:#2F92EE;'>#连花清瘟胶囊#</a>,这是<a href='/topic/show?id=6cce9642674' target=_blank style='color:#2F92EE;'>#钟南山#</a>院士做的研究成果,说实话,这个研究水平是相当低的,而且仅仅是<a href='/topic/show?id=568010405429' target=_blank style='color:#2F92EE;'>#体外研究#</a>,与临床研究完全不一样,也根本无法说明连花清瘟胶囊能够对抗<a href='/topic/show?id=46ce580e865' target=_blank style='color:#2F92EE;'>#新冠肺炎#</a>。但是,也不能苛求,就中药企业而言,这家公司已经是最好的了。再怎么说,人家还拿出一点证据,至少比<a href='/topic/show?id=a7533e66013' target=_blank style='color:#2F92EE;'>#双黄连#</a>强上很多倍, beContent=null, objectType=article, channel=null, level=null, likeNumber=168, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94569, encryptionId=4ea394569ed, topicName=连花清瘟胶囊), TopicDto(id=96426, encryptionId=6cce9642674, 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authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Fri Jan 29 09:54:20 CST 2021, time=2021-01-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1518820, encodeId=345e1518820f7, content=<a href='/topic/show?id=86f7945683c' target=_blank style='color:#2F92EE;'>#连花清瘟#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94568, encryptionId=86f7945683c, topicName=连花清瘟)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=356111182657, createdName=bluefate125, createdTime=Thu Mar 26 11:54:20 CST 2020, time=2020-03-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1557806, encodeId=0ff8155e80685, content=<a href='/topic/show?id=d2601533982' target=_blank style='color:#2F92EE;'>#Research#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15339, encryptionId=d2601533982, topicName=Research)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=96ab14929432, createdName=yangshch, createdTime=Thu Mar 26 11:54:20 CST 2020, time=2020-03-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1027534, encodeId=c6bf102e53439, content=新冠肺炎,疫情何时才能消失, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=公卫新人, createdTime=Tue Mar 24 23:54:20 CST 2020, time=2020-03-24, status=1, ipAttribution=)]
    2020-03-26 yangshch
  9. 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    2020-03-24 公卫新人

    新冠肺炎,疫情何时才能消失

    0

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