Sci Rep:输精管切除术后男性的长期安全、健康和精神状态研究

2018-11-05 AlexYang MedSci原创

输精管切除是一种有效的男性绝育手段,但是该技术在一个大群体中的长期影响仍旧不清楚。最近,有研究人员为了调查输精管切除术对健康的长期影响,他们在中国募集了485名经历过输精管切除的男性,并且募集了1940名没有经历输精管切除参与者作为对照。研究人员从老年男性症状量表(AMS)和其他调查问卷中获得了基础的信息后,采集了外周血样来评估激素水平、前列腺特异性抗原(PSA)和血液生化检验。研究人员通过多变量

输精管切除是一种有效的男性绝育手段,但是该技术在一个大群体中的长期影响仍旧不清楚。最近,有研究人员为了调查输精管切除术对健康的长期影响,他们在中国募集了485名经历过输精管切除的男性,并且募集了1940名没有经历输精管切除参与者作为对照。

研究人员从老年男性症状量表(AMS)和其他调查问卷中获得了基础的信息后,采集了外周血样来评估激素水平、前列腺特异性抗原(PSA)和血液生化检验。研究人员通过多变量线性回归分析发现,除了AMS中的体细胞评分(0.31, 0.02和0.61)、SF-36评分(18.8, 32.00和5.60)和角色情感(6.28, 10.34和2.22)以及精神健康(1.55, 3.08和0.02)这4个月因素外,其他因素与输精管切除均没有关系。分层分析表明了年龄的增加、抽烟和饮酒、城镇居民或者更高水平的教育条件下,男性的精神健康更差。输精管切除术对男性性激素水平没有长期的影响,并且没有增加PSA的水平。输精管切除对生活质量的影响主要反应在心理方面,表明了这些经历输精管切除的男性也许在专业的心理咨询下能够受益。

原始出处:

Kai Zhao, Li Wu, Xiangbin Kong et al. Long-term safety, health and mental status in men with vasectomy. Sci Rep. 24 Oct 2018.

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