Mater Sci Eng C Mater Biol Appl:氧化石墨烯/钴铁氧体磁性纳米粒子涂层可有效抗感染

2019-09-12 不详 网络

由于在改善其抗菌和抗腐蚀特性方面取得了明显进步,因此目前在表面保护涂层领域中需要基于材料的涂料。在这项工作中,我们开发了磁性氧化石墨烯(MGO)涂料,其中通过使用高能球磨(HEBM)掺入钴铁氧体(CF)和氧化石墨烯(GO)以及涂料。使用ESEM,AFM,拉曼,FTIR光谱研究MGO涂料的形态,元素和功能分析。 EDS和PIXE方法用于元素分析。热分析表明MGO薄膜在高达100°C时是稳定的。观察到

由于在改善其抗菌和抗腐蚀特性方面取得了明显进步,因此目前在表面保护涂层领域中需要基于材料的涂料。在这项工作中,我们开发了磁性氧化石墨烯(MGO)涂料,其中通过使用高能球磨(HEBM)掺入钴铁氧体(CF)和氧化石墨烯(GO)以及涂料。

使用ESEM,AFM,拉曼,FTIR光谱研究MGO涂料的形态,元素和功能分析。 EDS和PIXE方法用于元素分析。热分析表明MGO薄膜在高达100°C时是稳定的。观察到CF MNP的饱和磁化强度为76emu/g,MGP涂料的饱和磁化强度降低至12emu/g。用鼠伤寒沙门氏菌和大肠杆菌进行了制备的MGO涂料的详细抗菌研究。死亡评估显示对鼠伤寒沙门氏菌的杀菌率高达82%,而大肠杆菌则为20%。用SEM技术研究细菌细胞的形态学损伤。活性氧(ROS)生成实验和计算分析的流式细胞术分析支持诱导的ROS通过GO和CF与细菌蛋白的相互作用导致细菌膜损伤的机制,导致其功能的改变。

综上所述,观察到的结果表明,制备的MGO涂料可能是表面保护涂料纳米涂料领域的更好的候选材料。

原始出处:

Arun T, Verma SK, et al., Facile synthesized novel hybrid graphene oxide/cobalt ferrite magnetic nanoparticles based surface coating material inhibit bacterial secretion pathway for antibacterial effect. Mater Sci Eng C Mater Biol Appl. 2019 Nov;104:109932. doi: 10.1016/j.msec.2019.109932. Epub 2019 Jul 2.

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    2020-07-07 spoonycyy
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    2020-05-04 sunylz
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