Circ Cardiovasc Interv:我国非ST段抬高急性冠脉综合征现状:四成未评估早期风险,高危患者反而介入比例很低

2017-06-16 朱柳媛 中国循环杂志

改善中国心血管病治疗(CCC)项目组近期公布了一项最新结果,在我国非ST段抬高型急性冠脉综合征(NSTE-ACS)患者中,临床实际治疗情况与当前指南的治疗建议存在较大差距。

改善中国心血管病治疗(CCC)项目组近期公布了一项最新结果,在我国非ST段抬高型急性冠脉综合征(NSTE-ACS)患者中,临床实际治疗情况与当前指南的治疗建议存在较大差距。

首先,四成(40.6%)患者没有进行早期风险评估。

其次,有三成中高危患者未接受冠脉造影检查或介入治疗。仅63%的患者接受冠脉造影检查,58%接受冠脉介入治疗。

研究也发现了治疗悖论这一现象,越是高危的患者,应用介入治疗的比例反而较低。极高危患者中冠脉介入应用率最低,仅42%。

第三,仅11.1%的极高危患者和26.3%的高危患者在指南建议的时间内行冠脉介入治疗。

第四,11.7%的患者没有接受早期双联抗血小板治疗。

该研究中,患者死亡率为1.7%,12%的患者发生严重心血管事件。

不同治疗策略下的非ST段抬高急性冠脉综合征患者院内死亡率

就接受介入治疗的时间来看, 9%的患者在发病2小时内,14.8%在24小时内,31.3%在24-72小时内,44.8%在3天之后完成。

对于极高危患者,保守治疗的患者住院死亡率达到了9%。在<2小时,<24小时、24-72小时和>3天行介入治疗者的死亡率分别为6%、2%、1.5%和0.7%。

高危患者也有类似的趋势。保守治疗的患者住院死亡率为2.1%。<2小时,<24小时、24-72小时和>3天行介入治疗者的死亡率分别为1.6%、0.3%、0.2%和0.1%。

改善CCC ACS项目是一项全国性的注册登记研究,由中华医学会心血管病学分会和美国心脏协会于2014年协作开展,覆盖全国142家医院。该分析共纳入9953例NSTE-ACS患者。
 
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    2018-04-06 lxg951
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    2017-08-05 quxin068
  6. [GetPortalCommentsPageByObjectIdResponse(id=1819098, encodeId=f171181909866, content=<a href='/topic/show?id=de2d99226e2' target=_blank style='color:#2F92EE;'>#非ST段#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99226, encryptionId=de2d99226e2, topicName=非ST段)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=04ce158, createdName=lxg951, createdTime=Fri Apr 06 10:17:00 CST 2018, time=2018-04-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1926983, encodeId=a9f9192698348, content=<a href='/topic/show?id=be549922826' target=_blank style='color:#2F92EE;'>#非ST段抬高#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99228, encryptionId=be549922826, topicName=非ST段抬高)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5ed3112, createdName=echonoir, createdTime=Thu May 10 02:17:00 CST 2018, time=2018-05-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1955752, encodeId=a94b1955e5213, content=<a href='/topic/show?id=5b0b1022667b' target=_blank style='color:#2F92EE;'>#高危患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102266, encryptionId=5b0b1022667b, topicName=高危患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=05a2499, createdName=dzx0922889, createdTime=Fri Jun 30 21:17:00 CST 2017, time=2017-06-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2032392, encodeId=9f01203239280, content=<a href='/topic/show?id=f6159923e78' target=_blank style='color:#2F92EE;'>#非ST段抬高急性冠脉综合征#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99237, encryptionId=f6159923e78, topicName=非ST段抬高急性冠脉综合征)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3ff68, createdName=维他命, createdTime=Sat Aug 19 10:17:00 CST 2017, time=2017-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1938718, encodeId=82371938e180d, content=<a href='/topic/show?id=1c292818fd' target=_blank style='color:#2F92EE;'>#ASC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2818, encryptionId=1c292818fd, topicName=ASC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Sat Aug 05 23:17:00 CST 2017, time=2017-08-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1423027, encodeId=92b5142302e46, content=<a href='/topic/show?id=936c16863b5' target=_blank style='color:#2F92EE;'>#ST段抬高#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16863, encryptionId=936c16863b5, topicName=ST段抬高)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=91d33758978, createdName=gdsun, createdTime=Sun Jun 18 03:17:00 CST 2017, time=2017-06-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1430852, encodeId=302c143085250, content=<a href='/topic/show?id=f9b9e9124a8' target=_blank style='color:#2F92EE;'>#综合征#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79124, encryptionId=f9b9e9124a8, topicName=综合征)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Sun Jun 18 03:17:00 CST 2017, time=2017-06-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1624351, encodeId=add81624351c0, content=<a href='/topic/show?id=f27b16862d9' target=_blank style='color:#2F92EE;'>#ST段#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16862, encryptionId=f27b16862d9, topicName=ST段)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=676820671866, createdName=hyf035, createdTime=Sun Jun 18 03:17:00 CST 2017, time=2017-06-18, status=1, ipAttribution=)]
    2017-06-18 gdsun
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    2017-06-18 hyf035