BMJ:单髁与全膝关节置换患者预后差异研究

2019-02-26 zhangfan MedSci原创

研究认为,患者接受单髁人工膝关节置换术后多方面预后较好,但全膝关节置换患者的再手术风险降低

近日研究人员比较了单髁人工膝关节置换术(UKA)与全膝关节置换(TKA)对患者预后的影响。

本次研究为系统综述和荟萃分析研究,比较了过去20年中接受UKA 或TKA成年患者的预后差异,排除样本数目少于50人的研究。

60个研究纳入本次荟萃研究,其中7个来自随机对照研究,17个为数据库研究,36个为队列研究。研究发现,随机对照研究、数据库研究以及队列研究中,UKA患者的住院时间较TKA短1.20、1.43以及1.73天。依据病人自报告结果(PROMs),组间术后疼痛差异不显著,但UKA组患者功能评分较优。数据库研究发现,TKA组患者术后死亡风险增加(rr=0.27),主要是由于血栓事件以及主要血管风险导致的。TKA后早期全因二次手术风险增加,但5年后 UKA组再手术风险增加(2.50-5.95)。

研究认为,患者接受单髁人工膝关节置换术后多方面预后较好,但全膝关节置换患者的再手术风险降低。

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    2019-05-03 yxch48
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    2019-07-05 gaoxiaoe
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