Diabetes Care:抑郁和焦虑共存的2型糖尿病患者的死亡风险分析

2017-03-17 MedSci MedSci原创

既往研究报道,抑郁可显着增加2型糖尿病患者的死亡率,而焦虑往往伴随着抑郁同时发生。那么,抑郁和焦虑共存的2型糖尿病患者的死亡风险是如何的呢?

近日,糖尿病领域权威杂志Diabetes Care上发表了一研究文章,研究人员旨在评估抑郁和/或焦虑的2型糖尿病患者的死亡风险。

在这项研究中,研究人员采用了第二波挪威纵向人口健康研究(HUNT2)中64,177名挪威成人的数据,并结合挪威死亡登记的数据,评估了1995年至2013年参与调查研究的人员全因死亡率。通过Cox比例风险模型评定了大于18岁的2型糖尿病患者以及抑郁和/或焦虑共存的2型糖尿病患者的死亡风险。

此项研究结果显示:第一,存在抑郁或焦虑,或二者并存的2型糖尿病患者的死亡风险均是增加的;第二,单纯焦虑时死亡风险最低,抑郁焦虑共存时次之,单纯抑郁时死亡风险最高;第三,和焦虑及抑郁相关的高死亡风险主要发生在男性糖尿病患者,且男性糖尿病患者伴抑郁状态的死亡风险最高。

该研究说明,焦虑可以独立影响2型糖尿病患者的死亡风险,并可降低单纯抑郁状态下2型糖尿病患者的死亡风险。

原始出处

Kiyuri Naicker et al. Type 2 Diabetes and Comorbid Symptoms of Depression and Anxiety: Longitudinal Associations With Mortality Risk. Diabetes Care 2017 Mar; 40(3): 352-358.  https://doi.org/10.2337/dc16-2018

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