Int J Cardiol：ACS后WBCC增加与新发房颤有关！

2018-06-06 xing.T MedSci原创

由此可见，应进一步研究因ACS住院期间WBCC的增加应作为这些患者新发房颤潜在的简单预测因素。

在急性冠脉综合征（ACS）后，升高的白细胞计数（WBCC）（一种炎症反应的标志物）与房颤（AF）的发生发展之间关联的证据十分有限。近日，心血管领域权威杂志International Journal of Cardiology上发表了一篇研究文章，研究人员评估了住院期间WBCC与住院期间WBCC的变化与ACS住院期间新发房颤之间的关联。

在对医院病历进行系统评估中房颤的发生发展是基于典型的心电图变化。WBCC增加的计算方法是住院期间最大WBCC与入院时WBCC之间的差值。研究人员使用多因素logistic回归分析来调整几种可能混淆的人口统计学指标和临床变量，以评估WBCC以及随时间的变化与AF发生之间的关系。

研究对象的中位年龄（n=1325）为60岁，女性占31.8％，非西班牙裔白人占80.1％。ACS患者房颤发生率为7.3％。发生房颤的患者与未发生房颤的患者相比，入院时具有相似的WBCC，但在住院期间WBCC增加更多（6.0×109个细胞/L vs. 2.7×109个细胞/L，p<0.001）。在调整了几个潜在的混杂因素之后，WBCC的增加与AF的发生发展有关。这种关联在不同ACS亚型、接受治疗的类型以及急性症状发作时间的患者中同样可以观察到。

由此可见，应进一步研究因ACS住院期间WBCC的增加应作为这些患者新发房颤潜在的简单预测因素。

原始出处：

Hoang V. Tran,et al. Increase in white blood cell count is associated with the development of atrial fibrillation after an acute coronary syndrome.International Journal of Cardiology.2018. https://doi.org/10.1016/j.ijcard.2018.06.007

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#插入话题

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2018-08-15 仁者大医

#Cardiol#

32 0
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2018-06-07 王秀

学习了.涨知识了!

84 0
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2018-06-07 yaanren

#ACS#

30 0
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2018-06-07 若水125

#新发房颤#

38 0
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2018-06-06 sunfeifeiyang

阅

80 0
[GetPortalCommentsPageByObjectIdResponse(id=1781914, encodeId=9d601e8191431, content=<a href='/topic/show?id=5db8409ed8' target=_blank style='color:#2F92EE;'>#Cardiol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4097, encryptionId=5db8409ed8, topicName=Cardiol)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8e886, createdName=仁者大医, createdTime=Wed Aug 15 12:45:00 CST 2018, time=2018-08-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=322339, encodeId=a88532233974, content=学习了.涨知识了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDM9swhbgTo7nzqRKzMmzckmEoeTyLQVDCgjqsicjyhxPs0vPoYU6GsSYbCjSkNHicJkz3NL0a0EbUMVdNjkctXI6FocpGKaVr9E/0, createdBy=29392048316, createdName=王秀, createdTime=Thu Jun 07 23:58:21 CST 2018, time=2018-06-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1279264, encodeId=dc0612e92645b, content=<a href='/topic/show?id=316d1882bc' target=_blank style='color:#2F92EE;'>#ACS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1882, encryptionId=316d1882bc, topicName=ACS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=102a153, createdName=yaanren, createdTime=Thu Jun 07 22:45:00 CST 2018, time=2018-06-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1481379, encodeId=0fb614813e9b0, content=<a href='/topic/show?id=ce0258131ff' target=_blank style='color:#2F92EE;'>#新发房颤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58131, encryptionId=ce0258131ff, topicName=新发房颤)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=788d7780866, createdName=若水125, createdTime=Thu Jun 07 22:45:00 CST 2018, time=2018-06-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=321894, encodeId=df5c32189412, content=阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/07/a9772c74ffd6edc03a7f9af07b4747f6.jpg, createdBy=b3722138742, createdName=sunfeifeiyang, createdTime=Wed Jun 06 09:28:43 CST 2018, time=2018-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=321884, encodeId=6ec132188422, content=学习谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Wed Jun 06 09:24:34 CST 2018, time=2018-06-06, status=1, ipAttribution=)]
2018-06-06 龙胆草

学习谢谢分享

78 0

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Int J Cardiol：ACS后WBCC增加与新发房颤有关！

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