Semin Arthritis Rheu:超声诊断痛风的准确性

2018-04-30 xiangting MedSci原创

对已发表研究的meta分析表明,US的诊断准确性高、特异度高,在痛风的诊断中可以发挥重要作用。

这项研究旨在评估超声(US)对痛风的诊断性能。研究人员检索了Medline、Embase、Pubmed和Cochrane图书馆数据库,并根据痛风患者的双轮廓征、痛风石,暴雪或骨质侵蚀对US诊断的准确性进行了meta分析。共有11项研究可用于meta分析,包括938例痛风患者和788例对照(非痛风的炎性关节炎患者)。US的汇总灵敏度和特异度分别为65.1%([95%置信区间(CI):62.0-68.2]和89.0%(96.6-91.1)。阳性似然比、阴性似然比和诊断优势比分别为5.889 (3.365-10.30),0.359(0.266-0.485)和17.61(11.11-17.92)。US的曲线下面积为0.858,Q*指数为0.789,表明诊断准确率较高。Meta分析中发现一些研究间的异质性。Meta回归显示样本量、研究设计和诊断标准不是异质性的来源,亚组meta分析并未改变整体诊断的准确性。除双轮廓征外的US痛风石、暴雪或骨侵蚀征均不灵敏(54.3%,30.8%和51.6%),但作为诊断工具的特异度足够(93.2%,90.6%和93.3%)。对已发表研究的meta分析表明,US的

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    2018-05-02 zhaojie88
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    2018-04-30 紫迎馨

    谢谢分享

    0

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