JAMA Neurol:镰状细胞特征不会增加缺血性中风风险

2018-04-25 zhangfan MedSci原创

研究认为镰状细胞特征与非裔美国人缺血性中风风险无关,SCT并非中风的重要风险因素

与非西班牙裔白人相比,非裔美国人群的中风的风险增加,而镰状细胞特征(SCT)在非裔人群中的比例较高。近日研究人员考察了非洲裔美国人群中镰状细胞特征与缺血性中风风险之间的相关性。

本次研究为系统综述及荟萃分析研究,考察了4个大型前瞻性队列研究数据,利用Cox比例风险回归模型考察SCT与缺血性中风之间的相关性。

19464名非洲裔美国人参与研究,其中SCT人群1520人,非SCT人群17944人,缺血性中风患者620人,参与者平均年龄60.0岁,女性占73.0%。除SCT外其他缺血性卒中危险因素分布无显著性差异。未经调整前,SCT人群的缺血性卒中事件为每1000患者年2.9例,非SCT人群为3.2例。调整相关风险因素后,SCT人群的中风风险比为0.80(95% CI, 0.47-1.35; P=0.82)。

研究认为镰状细胞特征与非裔美国人缺血性中风风险无关,SCT并非中风的重要风险因素。

原始出处:


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    2018-08-17 yinhl1978
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    2018-04-25 清风拂面

    谢谢分享学习

    0

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    2018-04-25 戒馋,懒,贪

    谢谢分享学习了

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    2018-04-25 1ddf0692m34(暂无匿称)

    学习了.长知识

    0

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