Stroke:急性卒中患者生活方式因素与早期临床预后之间的关系

2017-01-20 xing.T MedSci原创

健康生活方式与较低的不良卒中预后风险相关,尤其是男性中。然而,体重过轻可能是特别需要关注的因素,在男性和女性中,它与不良预后风险增高之间存在相关性。

近日,卒中领域权威杂志Stroke上发表了一篇研究文章,研究人员旨在评估生活方式因素与早期不良卒中预后之间的相关性。

该研究共纳入了82597例经全国登记中心确认的参与者。在脑卒中入院时的收集的生活方式因素包括体重指数(kg/m2)、吸烟习惯和酒精摄入量,并对这些患者进行分组(分为健康、中度健康、中度不健康和不健康四组)。研究人员使用多元回归分析生活方式和预后之间的相关性。

该研究有18.3%的参与者发生严重卒中,7.8%的参与者患有肺炎,12.5%的参与者患有尿路感染,9.9%的参与者在30天内死亡。生活方式、脑卒中严重程度和死亡率之间的相关性根据性别有所不同。不健康的生活方式与较低的重症脑卒中(调整后的比值比为0.73;95%可信区间为0.63–0.84)和男性30天的死亡率(调整后的比值比为0.71;95%可信区间为0.58–0.87)风险相关,但在女性中不存在这样的相关性(重症脑卒中:调整后的比值比为1.14;95%可信区间为0.85–1.55;死亡率:调整后比值比为1.34;95%可信区间为0.90–1.99)。肺炎和尿路感染并无性别差异。不健康的生活方式与统计学上显著增加的发生住院肺炎(调整后的比值比为1.30;95%可信区间为0.98–1.73)或尿路感染(调整后的比值比为0.98;95%可信区间为0.72–1.33)风险之间并没有相关性。体重过轻与较高的30天死亡率相关(男性:调整后的比值比为1.71;95%可信区间为1.50–1.96;女性:调整后的比值比为1.46;95%可信区间为1.34–1.60)。

由此可见,健康生活方式与较低的不良卒中预后风险相关,尤其是男性中。然而,体重过轻可能是特别需要关注的因素,在男性和女性中,它与不良预后风险增高之间存在相关性。       

原始出处:

Annette Ingeman, et al. Lifestyle Factors and Early Clinical Outcome in Patients With Acute Stroke. Stroke. 2017. https://doi.org/10.1161/STROKEAHA.116.015784

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    2017-01-31 chunjianf

    卒中相关危险因素

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    2017-01-23 Anima

    卒中

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    2017-01-21 Lisa971

    因素相关性研究~

    0

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