Lancet Neurol:全球中枢神经系统肿瘤发病趋势研究——1990-2016

2019-02-21 zhangfan MedSci原创

研究认为,1990-2016年间全球中枢神经系统肿瘤的发病率呈现出上升趋势,发病率具有显著的地域特征,除诊疗因素外,环境和遗传风险因素可能是导致上述差异的重要原因

近日研究人员就1990-2016年间全球脑以及中枢神经系统肿瘤的发病率及变化趋势进行了系统研究。

研究就CNS肿瘤的发病率、死亡率以及劳力丧失修正寿命年(DALYs)进行了考察,CNS系统肿瘤包含脑膜恶性肿瘤、脑肿瘤、脊髓、脑神经等中枢神经系统恶性肿瘤,同时考察社会人口指数(SDI)对CNS-DALY的影响。

2016年,总计新确诊CNS肿瘤330000例,死亡227000例。1990-2016年间全球范围内,年龄标准计算的中枢神经系统肿瘤发病率增加17.3%。2016年,东亚地区男女人群CNS肿瘤的病例最多,其次是西欧和南亚,发病人数最多的国家为中国、美国和印度。CNS肿瘤导致全球770万DALY损失。1990-2016年间,因CNS肿瘤导致DALY损失下降10.0%,SDI最高1/5地区的年龄标准化DALY下降了10%,中等地区下降了10.2%,而SDI最低1/5地区的年龄标准化DALY上升了22.5%。

研究认为,1990-2016年间全球中枢神经系统肿瘤的发病率呈现出上升趋势,发病率具有显著的地域特征,除诊疗因素外,环境和遗传风险因素可能是导致上述差异的重要原因。

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    2019-02-27 yinhl1978
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    2019-07-22 howi
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