JCEM:超过50年的1型糖尿病血糖控制获益几何?

2017-08-02 xuyihan MedSci原创

之前的研究表明50年或以上的1型糖尿病患者(Medalists),其血糖控制水平与糖尿病并发症无关,除了心血管疾病(CVD),这与之前注册研究的记录相反。

之前的研究表明50年或以上的1型糖尿病患者(Medalists),其血糖控制水平与糖尿病并发症无关,除了心血管疾病(CVD),这与之前注册研究的记录相反。

为了进一步验证这些初步的研究结果并确定大队列层面上个人死亡的因素,Liane J. Tinsley等进行了横断面和纵向设计的研究。该研究纳入50年的Medalists患者,检测糖尿病血管和大血管的并发症及死亡率。

研究结果显示在Medalist患者中血糖控制与小血管并发症并不相关,在整个队列中与CVD显着相关。CVD是最大的致死病因,而糖化血红蛋白并不是死亡的独立预后因素。除此之外,运动锻炼减轻由CVD所致死亡风险。

几乎没有长病程的1型糖尿病大群体来检测长期暴露于高血糖的影响。该研究结果表明,血糖控制、并发症和死亡率在1型糖尿病老年患者中可能会有所改变。同时也表明仔细血糖控制在1型糖尿病老年患者中的必要性。

原始出处:


本文系梅斯医学(MedSci)原创编译整理,转载需授权!

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (4)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1777634, encodeId=9f7f1e77634e1, content=<a href='/topic/show?id=eb9610265ed' target=_blank style='color:#2F92EE;'>#JCEM#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10265, encryptionId=eb9610265ed, topicName=JCEM)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2a4439169927, createdName=smallant2015, createdTime=Tue Oct 10 05:13:00 CST 2017, time=2017-10-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2063016, encodeId=1337206301689, content=<a href='/topic/show?id=14fb10264d7' target=_blank style='color:#2F92EE;'>#JCE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10264, encryptionId=14fb10264d7, topicName=JCE)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e656479, createdName=achengzhao, createdTime=Thu Jan 04 05:13:00 CST 2018, time=2018-01-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1272959, encodeId=4a8c12e295947, content=<a href='/topic/show?id=2f468983351' target=_blank style='color:#2F92EE;'>#血糖控制#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89833, encryptionId=2f468983351, topicName=血糖控制)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ef84111, createdName=whlxd, createdTime=Fri Aug 04 10:13:00 CST 2017, time=2017-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=229395, encodeId=e1352293955d, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5Kzuf9u71gZhPYMiajRtENwicoAABeQtfXOlic8ibhYSy6DvJZWUDVtjRvTfqBffr1XJ6JLtFB5kHicthl/0, createdBy=d41c2055892, createdName=184****9840, createdTime=Thu Aug 03 05:50:58 CST 2017, time=2017-08-03, status=1, ipAttribution=)]
    2017-10-10 smallant2015
  2. [GetPortalCommentsPageByObjectIdResponse(id=1777634, encodeId=9f7f1e77634e1, content=<a href='/topic/show?id=eb9610265ed' target=_blank style='color:#2F92EE;'>#JCEM#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10265, encryptionId=eb9610265ed, topicName=JCEM)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2a4439169927, createdName=smallant2015, createdTime=Tue Oct 10 05:13:00 CST 2017, time=2017-10-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2063016, encodeId=1337206301689, content=<a href='/topic/show?id=14fb10264d7' target=_blank style='color:#2F92EE;'>#JCE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10264, encryptionId=14fb10264d7, topicName=JCE)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e656479, createdName=achengzhao, createdTime=Thu Jan 04 05:13:00 CST 2018, time=2018-01-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1272959, encodeId=4a8c12e295947, content=<a href='/topic/show?id=2f468983351' target=_blank style='color:#2F92EE;'>#血糖控制#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89833, encryptionId=2f468983351, topicName=血糖控制)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ef84111, createdName=whlxd, createdTime=Fri Aug 04 10:13:00 CST 2017, time=2017-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=229395, encodeId=e1352293955d, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5Kzuf9u71gZhPYMiajRtENwicoAABeQtfXOlic8ibhYSy6DvJZWUDVtjRvTfqBffr1XJ6JLtFB5kHicthl/0, createdBy=d41c2055892, createdName=184****9840, createdTime=Thu Aug 03 05:50:58 CST 2017, time=2017-08-03, status=1, ipAttribution=)]
    2018-01-04 achengzhao
  3. [GetPortalCommentsPageByObjectIdResponse(id=1777634, encodeId=9f7f1e77634e1, content=<a href='/topic/show?id=eb9610265ed' target=_blank style='color:#2F92EE;'>#JCEM#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10265, encryptionId=eb9610265ed, topicName=JCEM)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2a4439169927, createdName=smallant2015, createdTime=Tue Oct 10 05:13:00 CST 2017, time=2017-10-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2063016, encodeId=1337206301689, content=<a href='/topic/show?id=14fb10264d7' target=_blank style='color:#2F92EE;'>#JCE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10264, encryptionId=14fb10264d7, topicName=JCE)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e656479, createdName=achengzhao, createdTime=Thu Jan 04 05:13:00 CST 2018, time=2018-01-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1272959, encodeId=4a8c12e295947, content=<a href='/topic/show?id=2f468983351' target=_blank style='color:#2F92EE;'>#血糖控制#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89833, encryptionId=2f468983351, topicName=血糖控制)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ef84111, createdName=whlxd, createdTime=Fri Aug 04 10:13:00 CST 2017, time=2017-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=229395, encodeId=e1352293955d, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5Kzuf9u71gZhPYMiajRtENwicoAABeQtfXOlic8ibhYSy6DvJZWUDVtjRvTfqBffr1XJ6JLtFB5kHicthl/0, createdBy=d41c2055892, createdName=184****9840, createdTime=Thu Aug 03 05:50:58 CST 2017, time=2017-08-03, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=1777634, encodeId=9f7f1e77634e1, content=<a href='/topic/show?id=eb9610265ed' target=_blank style='color:#2F92EE;'>#JCEM#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10265, encryptionId=eb9610265ed, topicName=JCEM)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2a4439169927, createdName=smallant2015, createdTime=Tue Oct 10 05:13:00 CST 2017, time=2017-10-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2063016, encodeId=1337206301689, content=<a href='/topic/show?id=14fb10264d7' target=_blank style='color:#2F92EE;'>#JCE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10264, encryptionId=14fb10264d7, topicName=JCE)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e656479, createdName=achengzhao, createdTime=Thu Jan 04 05:13:00 CST 2018, time=2018-01-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1272959, encodeId=4a8c12e295947, content=<a href='/topic/show?id=2f468983351' target=_blank style='color:#2F92EE;'>#血糖控制#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89833, encryptionId=2f468983351, topicName=血糖控制)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ef84111, createdName=whlxd, createdTime=Fri Aug 04 10:13:00 CST 2017, time=2017-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=229395, encodeId=e1352293955d, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5Kzuf9u71gZhPYMiajRtENwicoAABeQtfXOlic8ibhYSy6DvJZWUDVtjRvTfqBffr1XJ6JLtFB5kHicthl/0, createdBy=d41c2055892, createdName=184****9840, createdTime=Thu Aug 03 05:50:58 CST 2017, time=2017-08-03, status=1, ipAttribution=)]
    2017-08-03 184****9840

    学习了谢谢分享

    0

相关资讯

Diabetes:HIIT能否减少1型糖尿病患者低血糖后认知障碍的发生?

2017年7月,发表在《Diabetes》的一项由荷兰和英国科学家进行的研究表明,高强度间歇训练(HIIT)降低1型糖尿病患者对后续低血糖的认知。

Nat Med:惊喜!NIH、川大、山大、南大联合发现,遍地都是的甘露糖竟然可以缓解1型糖尿病等自身免疫疾病

一说起食物中的糖,我们首先想到的通常是葡萄糖、果糖和蔗糖等等。这些对于糖尿病患者来说,真的是冤家一般的存在,不过,小编要是跟大家说,有一种“糖”可以抑制1型糖尿病的发展,大家敢不敢信? 这个神奇的“糖”就是葡萄糖的“异构体姐妹”——D-甘露糖。D-甘露糖天然存在于许多水果中,比如因为“保健”效果被炒得火热的蔓越莓。D-甘露糖在我们血液中的水平还不到葡萄糖的1/5,也没有葡萄糖那么受到重视。不

What?抗癌药用于1型糖尿病!

早期研究表明,抑制免疫系统并被批准用于治疗慢性骨髓性白血病和其他一些肿瘤的酪氨酸激酶抑制剂伊马替尼,可能有助于保护新诊断1型糖尿病人群的一些β细胞功能。美国加州大学旧金山分校的Stephen Gitelman教授在最近召开的美国糖尿病协会(ADA)2017科学会议上介绍了来自67名成年人的2年随机临床试验的初步1年发现。

Diabetes Care:胰岛素新发现或可逆转糖尿病

近日,来自瑞典乌普萨拉大学研究人员的研究结果发表于《糖尿病护理》的在线杂志中,在文章中,研究人员详细阐述了他们的发现,很多患糖尿病超过10年的1型糖尿病患者身体中仍然会分泌胰岛素。

Diabetic Med:关于在1型糖尿病患者中进行高胆固醇血症筛查的不同意见

近日,国际杂志《Diabetic medicine》上在线发表一项关于1型糖尿病是否需要筛查高胆固醇血症的研究。为了评估糖尿病专业人员使用现行实践调查评估1型糖尿病儿童的胆固醇筛查而国家健康与护理指南不推荐儿童1型糖尿病使用胆固醇筛查,而全国小儿糖尿病年度审查胆固醇指标(> 12年)作为关键指标。研究人员通过向280名儿童糖尿病临床医师协会的成员发送了一项在线调查,以评估儿童的胆固醇筛查实践。

Neurology:ω-3补充剂对1型糖尿病神经病变有何影响?

2017年6月,发表在《Neurology》的一项由加拿大科学家进行的为期12个月的先导试验,考察了ω-3补充剂对1型糖尿病(T1DM)神经病变的影响。