J Hypertens:85岁以上患者抗高血压治疗的保护效应!

2017-05-30 xing.T MedSci原创

由此可见,服用抗高血压药物治疗依从性较好可降低85岁或以上患者心血管疾病的发生风险,其益处包括心力衰竭和卒中,尽管不包括心肌梗死,并可用于全因死亡。

近日,高血压领域权威杂志Journal of Hypertension上发表了一篇研究文章,研究人员旨在评估85岁或以上的患者坚持服用降压药物是否会降低心血管事件风险。

研究人员在85岁或以上在2007年至2009年期间开始使用抗高血压药物治疗的患者进行了巢式病例对照研究。研究人员是通过使用意大利伦巴第(1000万)对所有公民都开放的数据库来确定研究对象。病例组是由从开始接触抗高血药物处方开始到2012年期间经历了因卒中心肌梗死(MI)或心脏衰竭出院或死亡的队列成员组成。每一名病例随机匹配了五名对照者。研究人员采用Logistic回归模型来评估坚持服用降压药物治疗与结局风险之间的相关性。一组年龄为70-84岁的患者被作为对照组。

研究人员发现相比于服用抗高血压药物依从性较低的患者,具有极好依从性的年龄在85岁或以上的老年人(平均88岁)发生死亡(47%;95%可信区间为5-57%)以及所有的组合结局(34%;95%可信区间为21-45%)的风险明显降低。心脏衰竭和卒中的发生风险也显著降低,而心肌梗死的风险并没有受到抗高血压药物的依从性的影响。在70-84岁的老年患者中也得到了类似的结果。

由此可见,服用抗高血压药物治疗依从性较好可降低85岁或以上患者心血管疾病的发生风险,其益处包括心力衰竭和卒中,尽管不包括心肌梗死,并可用于全因死亡。

原始出处:

Corrao, Giovanni;et al. Protective effects of antihypertensive treatment in patients aged 85 years or older.Journal of Hypertension. 2017. http://journals.lww.com/jhypertension/Abstract/publishahead/Protective_effects_of_antihypertensive_treatment.97756.aspx

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    2017-10-28 feather89
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    2017-05-31 cqykthl

    高龄患者血压控制与心血管时间关系

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    2017-05-31 Y—xianghai

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    学习了新知识

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