Sci Rep:口腔细菌不仅影响牙齿健康还会增加中风风险

2016-02-19 佚名 生物谷

在一项对入院治疗的急性中风病人进行的研究中,研究人员对特定类型中风与口腔细菌之间的关系有了更加深入的认识。来自日本大阪和美国路易斯维尔大学的研究人员共同进行了这项研究,相关结果发表在自然出版集团旗下期刊scientific reports上。 在这项研究中,研究人员发现在发生脑内出血的病人中,有26%的病人唾液中存在一种特定类型的细菌——CNM阳性变形链球菌。在其他类型的中风病人中,只有6%的病

在一项对入院治疗的急性中风病人进行的研究中,研究人员对特定类型中风与口腔细菌之间的关系有了更加深入的认识。来自日本大阪和美国路易斯维尔大学的研究人员共同进行了这项研究,相关结果发表在自然出版集团旗下期刊scientific reports上。

在这项研究中,研究人员发现在发生脑内出血的病人中,有26%的病人唾液中存在一种特定类型的细菌——CNM阳性变形链球菌。在其他类型的中风病人中,只有6%的病人能够检测到该细菌的存在。

中风主要包括缺血性中风(因脑部血管受阻而导致)以及出血性中风(因脑部血管破裂而导致)。

研究人员还对MRI检测结果显示存在脑微出血的病人进行了分析,这些病人有可能会发展为痴呆同时存在脑内出血的可能,结果发现唾液中含有CNM阳性变形链球菌的病人相比于没有该细菌的病人存在更多数量的脑微出血。

文章作者提出假设,CNM阳性变形链球菌可能会与血管结合,而随着衰老以及高血压等情况的发生,血管逐渐变得脆弱,这就会促进脑部动脉破裂,导致小范围或大范围出血。

其中一位作者表示,这项研究表明口腔卫生对于脑部健康非常重要,人们需要关注一下自己的牙齿,不仅是为了牙齿健康也是为了脑和心脏的健康。这项研究以及该研究团队的其他相关工作表明口腔细菌可能参与几种类型中风的发生。

一些研究已经发现牙龈疾病与心脏疾病之间存在密切关联。2013年发表的一篇文章也曾经解释了导致牙龈疾病的口腔细菌是如何加重类风湿性关节炎。

研究人员指出,大众群体中有大约10%携带CNM阳性变形链球菌,这种细菌还会导致龋齿的发生。他们目前还在寻找其他可能影响脑健康的口腔细菌。

原始出处:

Shuichi Tonomura, Masafumi Ihara,et al.Intracerebral hemorrhage and deep microbleeds associated with cnm-positive Streptococcus mutans; a hospital cohort study.Sci Rep.Feb 5,2016

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    2016-02-21 zhouqu_8
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    2016-02-20 stupidox

    有意思

    0

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    2016-02-20 1de07360m07(暂无匿称)

    了解一下

    0

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