JAMA Cardiology:高血压新突破可以确定干预范围,有助于防患于未然

2018-03-22 Heather_z727 来宝网

高血压,异常的血压,与心脏病发作和中风的风险增加有关。许多医疗专业人士仍然认为,随着年龄的增长,血压的增量变化是正常的,而且是预料之中的。一项新的研究发表在《美国心脏病学杂志》中,在报告中,研究人员指出,收缩压经常超过120~125毫米汞柱可认定为高血压,这一结果与年龄无关。

【超过临界血压阈值就是高血压,不论年龄大小】高血压,异常的血压,与心脏病发作和中风的风险增加有关。许多医疗专业人士仍然认为,随着年龄的增长,血压的增量变化是正常的,而且是预料之中的。一项新的研究发表在《美国心脏病学杂志》中,在报告中,研究人员指出,收缩压经常超过120~125毫米汞柱可认定为高血压,这一结果与年龄无关。

这些结果与最近更新的美国心脏病学会和美国心脏协会高血压指南一致,该指南将高血压分类为大于130/80毫米汞柱。

“有一个广泛流行的观念:血压随时间逐渐增加是正常老化的一部分,我们想知道,对于血压升高的人,是否有高血压开始发展的临界点?。换句话说,如果高血压确实发生了,什么时候开始发生变化,它看起来是什么样子,我们又该如何预防?”

在这项研究中,研究人员调查了来自Framingham心脏研究的1252名参与者的数据,该研究包含了少数几组标准血压(BP)在一段较长时间频繁间隔进行的标准血压测量。研究小组将高血压发病定义为血压超过或等于140/90毫米汞柱。参加者根据年龄,高血压的诊断分类。

研究小组发现,在高血压患者中,高血压发病的血压轨迹在模式上相似。事实上,他们的血压水平大致保持稳定,直到他们走近120~125毫米汞柱范围内,上述血压迅速上升到高压的范围。这一发现是一致的,无论高血压发展在哪个年龄层,这表明血压高于这个水平可以代表一个临界阈值的血管重塑发生在体内。有趣的是,这种血压范围符合最近发布的指南,将高收缩血压的定义降低到130毫米汞柱。

“虽然我们的研究结果表明,努力保持最高血压数低于120毫米汞柱的潜在重要性,提供健康老龄,我们的研究结果表明,有些人能够保持一个非常正常的血压范围。”

研究人员发现,研究中的许多人都能保持收缩压低于120~125毫米汞柱,这种新的了解生命过程中血压趋势的方法可以通过激励医生在接近高血压水平时更加警惕来影响临床实践。需要进一步的研究来揭示高血压患者在高血压出现前的变化顺序,并确定干预措施的潜在益处。

原始出处:

Teemu J. Niiranen, Mir Henglin, Brian Claggett, et al. Trajectories of Blood Pressure Elevation Preceding Hypertension Onset: An Analysis of the Framingham Heart Study Original Cohort. JAMA Cardiology, March 21, 2018.

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    2018-03-24 易水河

    高瞻远瞩的好消息

    0

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    2018-03-22 12212a77m11暂无昵称

    谢谢.学习了!

    0

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    2018-03-22 清风拂面

    谢谢分享学习

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1724976, encodeId=0f061e2497659, content=<a href='/topic/show?id=9ee758586bb' target=_blank style='color:#2F92EE;'>#新突破#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58586, encryptionId=9ee758586bb, topicName=新突破)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=792a33728807, createdName=zxxiang, createdTime=Thu Aug 30 17:58:00 CST 2018, time=2018-08-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1781894, encodeId=73021e81894f4, content=<a href='/topic/show?id=5db8409ed8' target=_blank style='color:#2F92EE;'>#Cardiol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4097, encryptionId=5db8409ed8, topicName=Cardiol)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8e886, createdName=仁者大医, createdTime=Mon Dec 24 02:58:00 CST 2018, time=2018-12-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2069283, encodeId=a1c720692832f, content=<a href='/topic/show?id=125e40988d' target=_blank style='color:#2F92EE;'>#Cardiology#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4098, encryptionId=125e40988d, topicName=Cardiology)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=316c73, createdName=caoliehu, createdTime=Mon Oct 15 21:58:00 CST 2018, time=2018-10-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=299149, encodeId=7ae6299149d3, content=高瞻远瞩的好消息, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKibA62IFMeUJEmSyIe8DvYFeERuOsfrRd8iano7nENqQU1dRR3tqeQOUL3eqgYgEZRT2t2iaEsib0JEw/132, createdBy=66771693911, createdName=易水河, createdTime=Sat Mar 24 06:40:26 CST 2018, time=2018-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=298656, encodeId=65e7298656b1, content=谢谢.学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ae9a2304278, createdName=12212a77m11暂无昵称, createdTime=Thu Mar 22 16:30:50 CST 2018, time=2018-03-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=298640, encodeId=0312298640dd, content=谢谢分享学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Thu Mar 22 12:56:43 CST 2018, time=2018-03-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=298634, encodeId=7c5229863402, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/iaAVWEsIJUkA1ITy3uL0lhHUhyaJibWgFtH4KbJuaLbY2WUK33jgCFyoZ8Eqx7eE7hCuZhytc1C5GRrfjVXN8lYg/0, createdBy=fcb82149579, createdName=183****7028, createdTime=Thu Mar 22 12:37:25 CST 2018, time=2018-03-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=298630, encodeId=30542986309c, content=谢谢分享学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM7GibvIBibibnnnvpajk2stlDF5oichYahI6Bia8uxeTBFoPbdoHWebyXf9eal9FNgUF2lNcrwoZicM3BvQ/0, createdBy=a3742066385, createdName=戒馋,懒,贪, createdTime=Thu Mar 22 12:10:52 CST 2018, time=2018-03-22, status=1, ipAttribution=)]
    2018-03-22 183****7028

    学习

    0

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    2018-03-22 戒馋,懒,贪

    谢谢分享学习了

    0

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