J Periodon Res：龈沟液中的天青杀素作为慢性牙周炎的潜在生物标志物

2020-04-02 网络网络

天青杀素（Azurocidin）是口腔龈沟液(GCF)中的中性粒细胞衍生蛋白，可能与牙周病有关。本研究旨在评价天青杀素是否可作为慢性牙周炎的潜在生物标志物。

天青杀素（Azurocidin）是口腔龈沟液(GCF)中的中性粒细胞衍生蛋白，可能与牙周病有关。本研究旨在评价天青杀素是否可作为慢性牙周炎的潜在生物标志物。

研究纳入101名患者，分为两组：水平健康组(HP)48例，慢性牙周炎组(CP)53例。临床检测指标包括探诊深度(PD)、牙龈退缩(REC)、临床附着水平(CAL)、探诊出血(BOP)和菌斑指数(Pl)。纸尖收集GCF样本，ELISA法检测天青杀素含量。

结果发现，与HP组相比，CP组的临床参数和天青杀素水平有统计学意义(p<0.05)。 ELISA结果显示，天青杀素诊断准确性较高。

本研究的结果与之前的研究结果一致，牙周炎患者的天青杀素水平呈上升趋势。天青杀素是GCF中一种有潜力的牙周病生物标志物。

原始出处：

Dimitrios Nalmpantis， Azurocidin in gingival crevicular fluid as a potential biomarker of chronic periodontitis. Journal of periodontal research， 2020， March. Doi： 10.1111/jre.12703

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2020-10-15 hukaixun

#标志物#

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2020-08-21 ms8435843352634314

#龈沟液#

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2020-08-07 feather89

#PE#

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2020-04-04 piaojinhua

#慢性牙周炎#

37 0
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2020-04-04 医者仁心

#牙周#

28 0
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2020-04-04 zhu_jun9842

#生物标志#

26 0
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2020-04-04 zhu_jun9842

#生物标志#

25 0

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J Periodon Res：龈沟液中的天青杀素作为慢性牙周炎的潜在生物标志物

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