SCI REP:术前NLR与肿瘤相关因素可预测NF-PNET患者的淋巴结转移!

2017-12-13 xing.T MedSci原创

NLR、症状性诊断、肿瘤大小与淋巴结转移有关。这些结果表明术前NLR ≥1.80,肿瘤大小超过2.5cm 和症状性诊断与接受切除手术的NF-PNETs患者淋巴结转移独立相关。

淋巴结(LN)状态对胰腺神经内分泌肿瘤(PNETs)患者的生存是非常重要的。因此,对LN转移相关因素的研究具有重要的临床意义。

近日,Scientific reports杂志上发表了一篇研究文章,研究人员的目的是评估术前中性粒细胞与淋巴细胞比率(NLR)、血小板与淋巴细胞比率(PLR)以及可能的临床参数在无功能性PNETs(NF-PNETs)患者淋巴结转移中的预测价值。

研究人员回顾性审查了101例接受根治性切除和淋巴结清扫术的NF-PNET患者。研究人员确定了临床病理因素与LN转移及预后之间的关系。

研究人员发现二十七例(26.7%)患者有淋巴结转移。淋巴结转移与无疾病生存率独立相关(P=0.009)。根据接受者操作特征曲线,NLR、PLR以及肿瘤大小预测淋巴结转移的理想临界值分别为1.80、168.25和2.5cm。在多变量分析中,NLR(P=0.017)、症状性诊断(P=0.028)、肿瘤大小(P=0.020)与淋巴结转移有关。这些结果表明术前NLR ≥1.80,肿瘤大小超过2.5cm 和症状性诊断与接受切除手术的NF-PNETs患者淋巴结转移独立相关。

由此可见,这些结果有助于手术前进一步规划淋巴结切除术。

原始出处:


Bo Zhou,et al. Preoperative neutrophil-to-lymphocyte ratio and tumor-related factors to predict lymph node metastasis in nonfunctioning pancreatic neuroendocrine tumors.Scientific reports. 2017. https://www.nature.com/articles/s41598-017-17885-y

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    2018-01-22 仁医06
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    2017-12-16 深海的鱼

    学习学习学习

    0

  4. 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    2017-12-15 sodoo
  5. 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  6. 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    2017-12-15 yuandd
  7. 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  8. 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    2017-12-14 榄枷檬

    学习学习

    0

  9. 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    2017-12-14 明月清辉

    谢谢分享.学习了

    0

  10. 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    2017-12-14 刘煜

    谢谢分享.阅读

    0

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Oncotarget:中性粒细胞与淋巴细胞比值预测神经胶质瘤患者生存情况!

神经胶质瘤,是发生于神经外胚层的肿瘤。大多缓慢发病,自出现症状至就诊时间一般为数周至数月,少数可达数年。恶性程度高的和后颅窝肿瘤病史较短,较良性的或位于静区的肿瘤病史较长。

Ann Surg :NLR为HCC患者肝脏切除术后生存的独立预测因素

尽管相关报告认为,高中性粒细胞/淋巴细胞值(NLR)为各种肿瘤患者较差生存的预测因素,但尚未对肝细胞癌(HCC)患者进行过深入考察。对此,日本九州大学Ken Shirabe博士等人进行了一项研究,该研究针对因HCC而接受肝脏切除治疗的患者,旨在阐释术前NLR的预后价值。这项研究结果发表于2013年6月14日在线出版的《外科学年鉴》(Annals of Surgery)杂志上。该项回顾性研究共招募了

Neurology:脑缺血患者溶栓前中性粒细胞高,患者预后差

目的:为了确定缺血性卒中(IS)患者,静脉给予rtPA溶栓前,较高的中性粒细胞计数与症状性脑出血(sICH)和3月不良预后之间的关系。方法:在里尔和赫尔辛基群体研究中,给予IS患者rtPA治疗前,检测血液中白细胞,中性粒细胞以及淋巴细胞计数。主要终点为sICH(欧洲急性脑卒中Ⅱ定义)。次要终点为死亡以及3个月极好预后(mRS分数0-1或等于卒中前),良好预后(mRS分数为0-2或等于卒中前)。结果

SCI REP:OPNI和NLR在Crohn病术后并发症风险评估中的价值!

由此可见,OPNI与NLR具有显著负相关。术前1年吸烟、OPNI<39.8以及NLR≥4.1是CD术后并发症的独立危险因素。