BMJ:中度饮酒会引发大脑健康程度的下降

2017-06-07 生物谷 生物谷

最近一项发表在《BMJ》杂志上的研究表明,即使中度的饮酒也会导致慢性的大脑认知水平的下降。这一结果支持了目前英国对于降低饮酒量的建议,并对目前美国的饮酒量的限制提出了质疑。我们已经知道,大量的饮酒会导致大脑健康水平的下降,但很少有研究关注中度的饮酒对大脑健康的影响,而且其研究结果也不一致。因此,来自牛津大学与伦敦学院大学的研究者们希望研究清楚中等

最近一项发表在《BMJ》杂志上的研究表明,即使中度的饮酒也会导致慢性的大脑认知水平的下降。这一结果支持了目前英国对于降低饮酒量的建议,并对目前美国的饮酒量的限制提出了质疑。

我们已经知道,大量的饮酒会导致大脑健康水平的下降,但很少有研究关注中度的饮酒对大脑健康的影响,而且其研究结果也不一致。

因此,来自牛津大学与伦敦学院大学的研究者们希望研究清楚中等程度的饮酒是否对大脑的结构与功能有任何正面或者负面的影响。


(图片摘自www.pixabay.com)

他们收集了近30年来对550名健康人进行的每周饮酒量以及行为认知能力的调查数据,接受调查的人群在研究开始时的平均年龄为43岁,他们中没有酒精依赖的情况存在。这些参与者的大脑定期地接受了fMRI检测。

当然,还有其它一些因素会影响最终的结果,例如年龄、性别、教育程度、社会地位、身体锻炼情况与社交情况、抽烟、中风风险以及就医历史。通过排除这些因素的影响,研究者们发现较高程度的酒精摄入会伴随着海马体萎缩症状发生风险的上升,此外,相比于禁酒,轻度的饮酒对于症状的缓解并没有保护的作用。饮酒量越高,则大脑白质的完整程度越低、语言流畅度也会随之降低。

研究者们指出,他们的研究仅仅是观察性的,因此无法得出确切的因果关系,但这一研究的确揭示了长期饮酒伴随着大脑功能的退化,因此他们认为这些发现对大众的健康具有积极的影响。

原始出处:

Topiwala Anya, Allan Charlotte L, Valkanova Vyara, Zsoldos Enik, Filippini Nicola, Sexton Claire et al. Moderate alcohol consumption as risk factor for adverse brain outcomes and cognitive decline: longitudinal cohort study BMJ 2017; 357 :j2353

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    2017-11-03 gaoxiaoe
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    2017-06-07 ami

    酒精对神经系统的影响是肯定的。

    0

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