CHEST:肺癌早期生存中的种族和种族差异

2017-04-29 xiangting MedSci原创

缩小早期肺癌患者的种族和种族差异,不仅仅依赖于手术切除机会的平等性,还需要更好地管理和治疗吸烟相关并发症和其他疾病。

手术切除有希望治愈的早期黑人肺癌患者其总体生存率低于白人。研究人员进行了一项以人口为基础的研究,评价由竞争原因造成死亡的种族和种族差距,并评估其对早期肺癌患者总体生存差距的影响。

研究人员收集了2004年至2013年生存、流行病和结果注册机构登记的105,121例早期(IA,IB,IIA和IIB)肺癌患者生存时间数据,其中包括西班牙裔,非西班牙裔亚洲人,非西班牙裔黑人和非西班牙裔白人。使用竞争性风险回归模拟生存时间,并将性别、诊断年龄、种族、诊断阶段、病理、手术切除类型和放射顺序作为协变量。

调整人口学、临床和治疗特征,非西班牙裔黑人与非西班牙裔白人相比,总体生存率差(调整后的风险比[aHR]:1.05;95%置信区间[CI]:1.02,1.08),而西班牙裔和非西班牙裔亚洲人的总体生存率更好(aHR=0.93;95%CI:0.89,0.98和aHR=0.82;95%CI:0.79,0.86)。由于竞争性原因引起的死亡,如CVD和其他癌症,而非肺癌本身,导致非西班牙裔黑人总体生存差异(调整后的相对风险= 1.07; 95%CI:1.02,1.12)。

由此可见,缩小早期肺癌患者的种族和种族差异,不仅仅依赖于手术切除机会的平等性,还需要更好地管理和治疗吸烟相关并发症和其他疾病。

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    2017-09-27 Smile2680
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    2017-05-09 jyzxjiangqin

    肺癌早期生存中的种族和种族差异。

    0

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