Leuk Lymphoma:体重指数可以预测弥漫性大B细胞淋巴瘤的结局吗?

2017-05-02 常路 环球医学

体重指数可以预测弥漫性大B细胞淋巴瘤的结局吗?2017年7月,发表在《Leuk Lymphoma》的一项在中国进行的单中心回顾性研究对此进行分析。

体重指数可以预测弥漫性大B细胞淋巴瘤的结局吗?2017年7月,发表在《Leuk Lymphoma》的一项在中国进行的单中心回顾性研究对此进行分析。



该研究旨在评估体重指数(BMI)在预测中国弥漫性大B细胞淋巴瘤(DLBCL)患者结局上的预测价值。143名符合条件的患者于2008年1月~2015年5月入组。这些患者分为两组:74人低BMI组(BMI<23.0kg/m2),69人为高BMI组(BMI≥23.0kg/m2)。研究人员比较了两组患者的基线特征、初始响应程度和生存结局。两组患者已知的影响因素相似,而性别并非如此(P=0.023),但是性别并不是风险因素。BMI和初始响应程度间无相关性。较高BMI的患者倾向于有更好的总生存期(OS)(P=0.018),但并未发现无进展生存期(PFS)具有相关性(P=0.067)。研究人员也发现BMI对OS的性别依赖的影响,较高的BMI可增加女性患者的OS(P=0.027),但男性患者并无该相关性(P=0.310)。

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    2017-05-02 lovetcm

    结果可靠性受质疑

    0

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