J Rheumatol:系统性红斑狼疮早期再入院的原因和预测因子

2018-04-25 xiangting MedSci原创

1/3的SLE住院患者在30天内再入院。出院时识别具有高度特异性的高危人群特征,有助于减少这种费用高昂的结局。

这项研究调查了出院后30天内再入院的成年系统性红斑狼疮(SLE)患者的特征,以期找出早期再入院的原因。

这是一项回顾性病例对照研究,分析了Cedars-Sinai医学中心2.5年间(2012-2014年)SLE患者的所有住院病历。纳入根据第9版国际疾病分类被诊断为SLE并在初次住院的30天内再入院的患者。这段时间内没有再入院的SLE患者作为对照组。收集每个患者的人口学和临床指标,并使用Charlson合并症指数来表征合并症。使用系统性狼疮国际合作诊所/美国风湿病学会损伤指数(SDI)评估SLE的慢性损伤。使用多因素logistic回归分析逐步法来预测与再入院相关的因素。

共有455名患者的570次住院符合纳入和排除标准。其中,154名(34%)患者在初次住院后30天内再入院。早期再入院患者更有可能拥有政府资助的医疗保险,并且与SDI升高(OR 1.27,95%CI 1.1-1.48),血红蛋白降低(OR 0.82,95%CI 0.72-0.93)和白蛋白降低(OR 0.66,95%CI 0.47-0.91)显著相关。

该项研究中,1/3的SLE住院患者在30天内再入院。出院时识别具有高度特异性的高危人群特征,有助于减少这种费用高昂的结局。


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    2018-04-27 zhouqu_8
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    2018-04-25 九九消寒

    优质资源.共同学习

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    2018-04-25 13718711b3m

    学习了.获益匪浅.感谢分享

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