J Hypertens:脑卒中后急性期SBP和降压治疗对跌倒风险的影响

2018-12-12 xing.T MedSci原创

由此可见,该研究的结果表明急性卒中前两天内SBP自发降低。无论卒中类型、年龄和是否进行抗高血压治疗,SBP都会有所降低,并且卒中前7天内强化降压治疗与跌倒无关。

急性卒中后的血压变化尚未得到充分研究。近日,高血压领域权威杂志Journal of Hypertension上发表了一篇研究文章,该研究的目的是描述卒中患者急性期SBP的发展趋势,并研究在此阶段强化降压治疗是否与跌倒风险的短期预后相关。

该观察性研究是哥德堡秋季研究的子研究,纳入了421例连续入住卒中单元的患者。研究人员分析了受试者血压测量数据、抗高血压治疗和跌倒的医疗记录。重复测量数据的随机系数模型用于分析SBP的变化,并采用单变量Cox比例风险模型来估计预测因子对前10天内首次跌倒的影响。

在卒中发病后的前两天,所有卒中患者的平均SBP下降了14.9mmHg(95%CI为12.3至17.4,P<0.0001),并且在发病后2-7天进一步下降2.3mmHg(95%CI为-0.1至4.7,P=0.066)。无论是否进行抗高血压治疗,SBP的降低都具有统计学意义。急性卒中后第一周内强化降压治疗与跌倒风险之间没有关联。

由此可见,该研究的结果表明急性卒中前两天内SBP自发降低。无论卒中类型、年龄和是否进行抗高血压治疗,SBP都会有所降低,并且卒中前7天内强化降压治疗与跌倒无关。

原始出处:

Kjellberg, Sigvar.et al.SBP and antihypertensive treatment in the acute phase after stroke and its impact on the risk of falling. Journal of Hypertension. 2018. https://journals.lww.com/jhypertension/Abstract/publishahead/SBP_and_antihypertensive_treatment_in_the_acute.97304.aspx

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    2018-12-12 健健

    卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!

    0

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    2018-12-12 1ddf0692m34(暂无匿称)

    学习了,长知识

    0

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