JAHA:心脏植入式电子设备急性并发症的性别差异

2019-01-19 xiangting MedSci原创

女性出现急性CIED并发症的风险较高。

截至目前,很少有人群水平的研究分析过性别对心脏植入式电子设备(CIED)急性并发症的影响,CIED包括永久起搏器、植入式心律转复除颤器和心脏再同步治疗设备。

这里研究了2010至2015年期间年龄>18岁,植入新的永久性起搏器、植入式心律转复除颤器或心脏再同步治疗设备的澳大利亚或新西兰居民。收集标准化变量,其中包括患者的人口学特征、主要和次要诊断、进行的手术和出院状态。诊断和手术按照国际疾病分类第10版(ICD-10)和澳大利亚健康干预分类进行编码。主要终点是住院期间或出院后90天内主要CIED相关并发症的发病率,使用多重logistic回归评估性别的影响。

共纳入81304例新CIED植入(包括61658例永久起搏器,12097例植入式心律转复除颤器,7574例心脏再同步治疗设备)(38%为女性)。总体而言,8.5%的女性和8.0%的男性出现CIED并发症(P=0.008)。在调整年龄、手术敏锐度和合并症后,男女间的差异仍然显著(优势比1.10,95%CI:1.04-1.16,P<0.001)。CIED并发症发生率的差异主要由院内胸腔引流率(女性1.2%vs男性0.6%,P<0.001;校正比值比1.86,95%CI:1.59-2.17,P<0.001)和心包引流率过高引起(女性0.3%vs男性0.1%,P<0.001;校正比值比2.17,95%CI:1.48-3.18,P<0.001)。

女性出现急性CIED并发症的风险较高。需要改进植入技术以尽量减少女性植入相关并发症的风险。

原始出处:

Katherine Moore. Sex Differences in Acute Complications of Cardiac Implantable Electronic Devices: Implications for Patient Safety. JAHA. 16 January 2019.

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    2019-11-21 villahu
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    2019-05-02 丁鹏鹏
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    2019-01-26 jyzxjiangqin

    心脏植入式电子设备。

    0

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    2019-01-21 zhaohui6731
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    2019-01-21 jiyangfei
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    2019-01-20 flysky120

    学习新知识谢谢

    0

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