Hear Res:单边听力损失儿童听力和语言结果研究

2018-04-06 AlexYang MedSci原创

因为新生儿听力筛选过程,单边听力损失(UHL)儿童在很小的年龄时就能够被诊断。从传统的观点看,这些儿童在听力和语言发展过程中会存在障碍风险。儿童早期-出生前几个月的临时群体可利用信息很少。最近,有研究人员在一个早期鉴定的患有UHL的儿童临时性群体中调查了听力和语言学习结果,并且与他们的同龄的学前年龄的轻度双边听力损失和正常听力损失儿童进行了比较。研究人员在4年时间内搜集了患有单边、双边听力损失和具

因为新生儿听力筛选过程,单边听力损失(UHL)儿童在很小的年龄时就能够被诊断。从传统的观点看,这些儿童在听力和语言发展过程中会存在障碍风险。儿童早期-出生前几个月的临时群体可利用信息很少。最近,有研究人员在一个早期鉴定的患有UHL的儿童临时性群体中调查了听力和语言学习结果,并且与他们的同龄的学前年龄的轻度双边听力损失和正常听力损失儿童进行了比较。

研究人员在4年时间内搜集了患有单边、双边听力损失和具有正常听力儿童的相关数据。他们的研究是48个月大儿童的代表性研究。研究在2010年到2015年总共包括了120名儿童(38名单边听力损失、31名轻度双边听力损失和51名正常听力)。研究发现,在大多数测量中,患有UHL的儿童的表现要比轻度双边听力损失组和正常听力组更差。所有患有听力损失组的表现均差于正常听力对照组。然而,在他们的研究中的语言测量方面,正常听力组的平均标准的得分要比标准测量方法要高。特别的是,患有UHL的儿童在48个月大时,与正常听力对照组相比,展现出了在功能性听力和在接受和表达语言技巧方面的缺陷。但他们在词汇认知和语言组织方面与他们的听力正常同龄人差异不显著。

最后,研究人员指出,尽管在早期生命阶段得到了鉴定,患有UHL的儿童与正常听力同龄人相比,在功能性听力和认识和表达语言发展方面仍旧表现出了滞后的趋势。

原始出处:

Fitzpatrick EM, Gaboury I, Durieux-Smith A et al. Auditory and language outcomes in children with unilateral hearing loss. Hear Res. 13 Mar 2018.

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    2018-04-08 ysjykql
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    2018-04-08 yangjxjc
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    2018-04-07 lou.minghong

    学习谢谢分享!

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    2018-04-07 lou.minghong

    学习

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    2018-04-06 龙胆草

    学习谢谢分享

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老龄化,噪音,顺铂毒性或其他刺激引起的听力损失影响着全球范围内的3.6亿人,但至今为止,还没有预防或治疗听力损失的药物得到食品和药物管理局的批准。

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先天性巨细胞病毒(CMV)感染是感官听力损失形成的主要原因。根据法律要求,美国康涅狄格州新生儿听力听力筛选失败的要要进行CMV感染测试。该项针对性的筛选是具有争议的,因为大多数具有先天性CMV感染的儿童都是无症状的,并且CMV相关的听力损失发生较晚。最近,有研究人员利用了唾液聚合酶链式反应(PCR)试验(由尿液PCR确定)来检测CMV。在该研究中,他们报道了第一年的4个筛选计划的结果。研究发现,在

Sci Rep:IDH2功能丧失能够加速年龄相关的听力损失

异柠檬酸脱氢酶(IDH)2参与了TCA循环并且能够催化异柠檬酸到α-酮戊二酸以及NADP+到NADPH的转化。在线粒体中,IDH2通过提供NADPH到谷胱甘肽还原酶(GSR)和硫氧还蛋白还原酶(TXNRD2),同样在保护线粒体组分免受氧化胁迫上具有重要的作用。最近,有研究人员报道了Idh2功能的丧失能够加速年龄相关的听力损失,这也是雄性小鼠最为常见的听力损伤形式。并且在24个月大的Idh2-/-小

Maturitas:在老年人中,言语和高频率听力损失以及抑郁、焦虑和压力之间的相关性研究

年龄相关的听力损失(ARHL)和抑郁被认为是导致老年人残疾的主导原因。最近,有研究人员进行了一个代表性的研究,调查了老年人中言语严重度和高频听力损失与抑郁、焦虑和压力之间的关系。研究包括了151名参与者(73名男性和78名女性,平均年龄为64.44±10.77岁)。研究人员根据他们的更好的耳朵听力(0.5, 1, 2和4kHz)和高频率(6和8kHz)听力阈值,将他们分成了3个小组:正常听力组、轻