JCO：锻炼可降低肥胖乳腺癌幸存者心血管风险

2018-02-10 国际循环编辑部国际循环

一项最新研究表明，运动可帮助超重和肥胖的乳腺癌幸存者改善逆转综合征。该项研究发表于1月22日的《临床肿瘤学杂志》（Journal Of ClinicalOncology）。

一项最新研究表明，运动可帮助超重和肥胖的乳腺癌幸存者改善逆转综合征。该项研究发表于1月22日的《临床肿瘤学杂志》（Journal Of ClinicalOncology）。

美国洛杉矶南加州大学肿瘤综合研究中心主任Christina Dieli-Conwright及其同事对100例久坐不动的超重或肥胖妇女进行了为期四个月的研究。受试者被随机分配至运动组：每周三次指导性锻炼，包括负重阻力训练和中等强度有氧运动，或非运动组：坚持他们平时的活动水平。

基线时，77%的女性达到了代谢综合征标准；试验结束时，运动组只有15%的受试者仍有代谢综合征，而非运动组有80%。Christina Dieli-Conwrigh指出，心脏病是乳腺癌幸存者死亡的主要原因。该项研究发现，锻炼可改善与心脏病相关的危险因素。运动可改善心脏、血管、肺和肌肉功能，再加上脂肪的减少，可减轻肥胖对身体造成的压力。

这一过程对于可能肥胖的乳腺癌幸存者至关重要，但也受到诸如疲劳、抑郁和久坐行为等治疗不良反应的影响。他们现心血管风险更高，但可从锻炼中得到很大好处。

除了逆转代谢综合征，这些锻炼还与血压下降、高密度脂蛋白胆固醇（HDL-C）升高和甘油三酯水平降低有关。

该项研究的局限性包括试验中监督锻炼的结果可能并不能反映出如果女性试图独自锻炼会发生什么；以及这项研究没有根据女性患乳腺癌的类型来研究运动的影响。

美国西弗吉尼亚大学健康科学中心Linda Vona-Davis评论认为，锻炼和健康饮食可能同样有效。采用体育锻炼的生活方式已被证明可改善乳腺癌妇女的体能和生活质量。

原始出处：

Christina M. Dieli-Conwright, et al. Effects of Aerobic and Resistance Exercise on Metabolic Syndrome, Sarcopenic Obesity, and Circulating Biomarkers in Overweight or Obese Survivors of Breast Cancer: A Randomized Controlled Trial. Journal of Clinical Oncology. Jan 22, 2018.

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2018-03-04 lidong40

#JCO#

29 0
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2018-02-15 1209e435m98(暂无昵称)

学习了.谢谢分享

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2018-10-20 ms5353107019656438

#血管风险#

27 0
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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/01/15/8213228fe923915543544ad3da7e1c64.jpg, createdBy=6bd82014262, createdName=秀红, createdTime=Sun Feb 11 06:06:20 CST 2018, time=2018-02-11, status=1, ipAttribution=)]
2018-02-12 惠映实验室

学习.谢谢分享.

101 0
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2018-02-12 1ddf0692m34(暂无匿称)

学习了.涨知识

85 0
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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/01/15/8213228fe923915543544ad3da7e1c64.jpg, createdBy=6bd82014262, createdName=秀红, createdTime=Sun Feb 11 06:06:20 CST 2018, time=2018-02-11, status=1, ipAttribution=)]
2018-02-11 wzb521zf

一起学习学习

65 0
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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/01/15/8213228fe923915543544ad3da7e1c64.jpg, createdBy=6bd82014262, createdName=秀红, createdTime=Sun Feb 11 06:06:20 CST 2018, time=2018-02-11, status=1, ipAttribution=)]
2018-02-11 wqkm

^_^^_^

78 0
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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/01/15/8213228fe923915543544ad3da7e1c64.jpg, createdBy=6bd82014262, createdName=秀红, createdTime=Sun Feb 11 06:06:20 CST 2018, time=2018-02-11, status=1, ipAttribution=)]
2018-02-11 1209e435m98(暂无昵称)

学习了.谢谢分享

26 0
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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/01/15/8213228fe923915543544ad3da7e1c64.jpg, createdBy=6bd82014262, createdName=秀红, createdTime=Sun Feb 11 06:06:20 CST 2018, time=2018-02-11, status=1, ipAttribution=)]
2018-02-11 yjs木玉

好好好好好好好好

17 0
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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/01/15/8213228fe923915543544ad3da7e1c64.jpg, createdBy=6bd82014262, createdName=秀红, createdTime=Sun Feb 11 06:06:20 CST 2018, time=2018-02-11, status=1, ipAttribution=)]
2018-02-11 秀红

学习了

25 0