J Stomatol Oral Maxillofac Surg:低强度激光治疗可促进牵张成骨的效果

2018-06-22 MedSci MedSci原创

本研究旨在探究低水平激光疗法(LLLT)在牵张成骨(DO)中的组织病理学效应。 研究纳入了20只成年雌性新西兰白兔。在全身麻醉下进行单侧下颌体截骨术。将定制的外部牵引器被放置在兔子的右下颌骨上。五天的潜伏期后,每天以1毫米/天的速度牵拉,持续5天。研究组动物在每个牵张器从六个不同的点透皮接触LLLT。对照组未暴露于激光照射。光照15和30天后处死动物并在光学显微镜下处理下颌骨用于组织病理学检查。用

本研究旨在探究低水平激光疗法(LLLT)在牵张成骨(DO)中的组织病理学效应。

研究纳入了20只成年雌性新西兰白兔。在全身麻醉下进行单侧下颌体截骨术。将定制的外部牵引器被放置在兔子的右下颌骨上。五天的潜伏期后,每天以1毫米/天的速度牵拉,持续5天。研究组动物在每个牵张器从六个不同的点透皮接触LLLT。对照组未暴露于激光照射。光照15和30天后处死动物并在光学显微镜下处理下颌骨用于组织病理学检查。用半定量4点量表分析骨愈合。

结果显示,光照15天后,研究组兔的成骨细胞活性和血管化程度高于对照组。对照组的软骨细胞活性在15天和30天均明显高于研究组。光照15天后,研究组成骨细胞活性和骨小梁形成明显高于对照组。

综上所述,该研究结果表明,在牵张成骨的激活期中使用LLLT可诱导骨愈合,并在骨愈伤组织中形成较少的软骨组织来刺激牵引骨成形的早期阶段的骨修复。

原始出处:

Gurler G, Gursoy B. Investigation Of Effects Of Low Level Laser Therapy In Distraction Osteogenesis. J Stomatol Oral Maxillofac Surg. 2018 Jun 6. pii: S2468-7855(18)30122-8. doi: 10.1016/j.jormas.2018.05.006.

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    2018-10-13 hyf028
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    2019-01-27 小几洁
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  5. 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    2018-06-24 oliver169
  7. 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encryptionId=e95954093cd, topicName=成骨)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Sun Jun 24 09:46:00 CST 2018, time=2018-06-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1434717, encodeId=bb6f1434e17b2, content=<a href='/topic/show?id=817f66e686a' target=_blank style='color:#2F92EE;'>#激光治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66768, encryptionId=817f66e686a, topicName=激光治疗)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Sun Jun 24 09:46:00 CST 2018, time=2018-06-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=326183, encodeId=77dc3261838d, content=学习一下谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLGSUSR8zwnWWLT4FMl5XH8S58HuZslVkLsAPbXDXaliagK7TOxQfmngKibG1yrDonepCLDkcxGk8hS/0, createdBy=b8282062892, createdName=changjiu, createdTime=Fri Jun 22 22:52:04 CST 2018, time=2018-06-22, status=1, ipAttribution=)]
    2018-06-24 zhaojie88
  8. 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  9. 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beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLGSUSR8zwnWWLT4FMl5XH8S58HuZslVkLsAPbXDXaliagK7TOxQfmngKibG1yrDonepCLDkcxGk8hS/0, createdBy=b8282062892, createdName=changjiu, createdTime=Fri Jun 22 22:52:04 CST 2018, time=2018-06-22, status=1, ipAttribution=)]
    2018-06-22 changjiu

    学习一下谢谢

    0