Am J Emerg Med:入院乳酸水平可能预测动脉瘤性蛛网膜下腔出血死亡率

2016-05-28 phylis 译 MedSci原创

背景:动脉瘤性蛛网膜下腔出血(SAH)是出血性脑卒中的最具破坏性的形式。主要根据初步临床表现预测死亡的发生。初始血清乳酸水平已被证明可以预测死亡和疾病的严重程度。初始血清乳酸可能是一个客观的预测因子或死亡率。方法:回顾性分析一个大型学术中心超过42个月的,动脉瘤性蛛网膜下腔出血的患者。。收集的数据包括人口统计数据,临床数据,血清和临床预后数据。在基线时收集流行病学资料,并对住院病人进行随访。研究者

背景:动脉瘤性蛛网膜下腔出血(SAH)是出血性脑卒中最具破坏性的形式。主要根据初步临床表现预测死亡的发生。初始血清乳酸水平已被证明可以预测死亡和疾病的严重程度。初始血清乳酸可能是一个客观的预测因子或死亡率。

方法:回顾性分析一个大型学术中心超过42个月的,动脉瘤性蛛网膜下腔出血的患者。收集的数据包括人口统计数据、临床数据、血清和临床预后数据。在基线时收集流行病学资料,并对住院病人进行随访。研究者比较死亡组(组A)和幸存者组(组B)的数据。

结果:共有249例患者。死亡率为21.5%。两组平均年龄分别为57岁(A组)和55岁(B组)。入院时平均血清乳酸水平为3.5 ±2.5(A组),2.2 ±1.6(B组)。范围是0.01至14.7。校正Hunt和Hess等级后,多变量分析表明乳酸水平是死亡的独立预测因子。

结论:动脉瘤性蛛网膜下腔出血患者,入院时血清乳酸水平可能预测死亡的发生,并且可能是疾病严重程度的指标。目前,乳酸水平不是SAH患者常规检查项目,未来常规血液学检查可能作为附加的预后指标。

原始出处:

Aisiku IP, Chen PR, et al. Admission serum lactate predicts mortality in aneurysmal subarachnoid hemorrhage. Am J Emerg Med. 2016 Apr.


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    2016-10-14 ylzr123

    好文,值得推荐。

    0

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