Neuroradiology:慢性单侧颅脑大血管狭窄闭塞性病变患者深部白质相关研究。

2017-09-07 shaosai MedSci原创

本研究旨在验证是否在单侧慢性颅脑大血管狭窄闭塞性病变患者深部白质在多体素磁共振(MR)波普成像表观颅脑温度成像与正电子发射断层成像(PET)脑血流(CBF)和代谢成像间具有相关性,并将结果发表在Neuroradiology上。

本研究旨在验证是否在单侧慢性颅脑大血管狭窄闭塞性病变患者深部白质在多体素磁共振(MR)波普成像表观颅脑温度成像与正电子发射断层成像(PET)脑血流(CBF)和代谢成像间具有相关性,并将结果发表在Neuroradiology上。

本研究共纳入了35例患者,并行质子MR波谱成像和15O-PET检查,分别得到表观颅脑温度和CBF及代谢成像。将一组5 × 5感兴趣区(ROIs)放置在每侧大脑半球半卵圆中心区域。利用图像分析软件将PET图像与放置ROIs的MR图像匹配并进行自动分割。

结果为,共有175体素对放置在深部白质,颅脑温度差异(受累半球-对侧半球,ΔBT)与脑血流量(CBF)(r = 0.570)和氧摄取分数(OEF)比(受累侧半球/对侧半球)(r = 0.641)具有相关性。在每一例患者中,去除包含缺血灶或脑脊液的体素并计算平均体素对的值。平均ΔBT与平均CBF(r = - 0.376)、平均CBV(r = 0.702)和平均OEF比(r = 0.774)具有相关性。

多体素MR波谱表观颅脑温度成像与单侧慢性颅脑大血管狭窄或闭塞患者深部白质的CBF和代谢具有相关性。

原始出处:


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    2018-06-15 kkunny
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    2017-09-09 lietome24

    感谢小编为我们准备了如此丰盛的精神大餐.同时也向作者致谢!认真学习了.点赞!

    0

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    2017-09-08 海棠胜雪

    学习了

    0

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    2017-09-08 shaosai

    好好学习.涨知识

    0

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    2017-09-08 baihao215

    高大上.学习了

    0

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    2017-09-07 1e0f8808m18(暂无匿称)

    好文章.学习了.

    0