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ANN SURG：腹腔腹与开腹远端胃癌D2根治术对比

2018-03-25 MedSci MedSci原创

胃癌腹腔镜开腹
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D2淋巴结清扫是晚期胃癌的标准治疗方案。尽管腹腔镜辅助远端胃切除在早期胃癌治疗中已得到广泛应用，其在晚期胃癌中的可行性尚未得到证实。ANN SURG近期发表了一篇文章，评估了腹腔镜辅助远端胃切除术联合D2淋巴结清扫与开腹远端胃切除术对比治疗晚期胃癌的效果。

D2淋巴结清扫是晚期胃癌的标准治疗方案。尽管腹腔镜辅助远端胃切除在早期胃癌治疗中已得到广泛应用，其在晚期胃癌中的可行性尚未得到证实。ANN SURG近期发表了一篇文章，评估了腹腔镜辅助远端胃切除术联合D2淋巴结清扫与开腹远端胃切除术对比治疗晚期胃癌的效果。

分期T2-T4a且N0-2的远端胃癌患者随机1：1分为腹腔镜组和开腹组。主要的研究终点为淋巴结清扫不符合率，主要用来评估可行性。次要的研究终点包括3年无病生存率和5年总生存率，并发症发生情况等。2010年6月到2011年10月间，共204例患者入组且接受腹腔镜手术或开腹手术。这些患者中，196例进行了最后的分析。腹腔镜服和开腹淋巴结清扫总不符合率无显着差异。亚组分析表明，Ⅲ期胃癌患者中腹腔镜组不符合率显着高于开腹组。两组间3年无病生存率无差异。两组间术后并发症率也无显着差异。

文章最后认为，腹腔镜辅助远端胃切除术治疗晚期胃癌是可行的。亚组分析数据表明需要针对Ⅲ期胃癌进行进一步研究。

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    2018-11-17 xjy02

    #胃癌D2根治术#

    0

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    2018-06-04 huangdf

    #D2根治术#

    0

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    2018-03-27 owlhealth

    不错耶.学习了

    0

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    2018-03-27 bluefate122

    #根治术#

    0

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    2018-03-27 jeanqiuqiu

    #根治#

    0

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