J Oral Rehabil:钛种植体周钛颗粒的释放情况

2018-10-17 MedSci MedSci原创

种植体周围炎被认为是一种细菌感染性疾病,但最近的研究表明,钛可以与细菌一起加重炎症。种植体周围炎和牙周炎(对照)组织的Ti含量未知。本研究旨在研究严重种植体周围炎或无Ti暴露的对照组组织中的钛(Ti)含量。 本研究纳入13例种植体炎患者和11例牙周炎患者。根据牙科记录评估疾病严重程度。从两组中取活组织检查,并用电感耦合等离子体质谱(ICP-MS)对Ti含量进行化学分析。此外,研究招募了2名种

种植体周围炎被认为是一种细菌感染性疾病,但最近的研究表明,钛可以与细菌一起加重炎症。种植体周围炎和牙周炎(对照)组织的Ti含量未知。本研究旨在研究严重种植体周围炎或无Ti暴露的对照组组织中的钛(Ti)含量。

本研究纳入13例种植体炎患者和11例牙周炎患者。根据牙科记录评估疾病严重程度。从两组中取活组织检查,并用电感耦合等离子体质谱(ICP-MS)对Ti含量进行化学分析。此外,研究招募了2名种植体周围炎患者和2名牙周炎患者,并用显微镜(LM),透射电子显微镜(TEM)和扫描电子显微镜(SEM)进行显微镜分析,并进行元素分析以研究钛颗粒的存在。

结果显示,尽管进行了种植体周围的治疗,但所有患者均丧失了一个或多个种植体。种植体周围炎组织含有明显高于对照组中的Ti浓度,平均值±SD分别为98.7±85.6μg/g和1.2±0.9μg/g。在种植体周围炎和对照组活组织检查中发现了颗粒状金属,但元素分析只证实种植体周围组织中存在Ti。

综上所述,该研究结果表明,种植体周围组织中存在高含量的颗粒和亚微米Ti。种植体周围粘膜中的这些高Ti含量可能会加重炎症,或可影响种植体周围炎治疗的预后。

原始出处:

Pettersson M, Pettersson J, et al., Titanium release in peri-implantitis. J Oral Rehabil. 2018 Oct 16. doi: 10.1111/joor.12735.

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    2019-07-25 30397613
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    2018-11-27 huangdf
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    2018-11-07 小几洁
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    2018-10-19 qjddjq