J Periodontal Res: 心血管疾病患者牙齿脱落、全身炎症与牙周病原体抗体滴度的关系

2018-04-03 MedSci MedSci原创

众所周知,牙周炎与心血管疾病(CVD)之间有很强的联系。牙齿脱落反映了牙周炎等口腔疾病的末期状况。已知具有特定牙周病原体的感染是影响CVD发展的可能性因素。本研究的目的是评估CVD患者剩余牙数量与全身炎症状况之间的关系。

众所周知,牙周炎与心血管疾病(CVD)之间有很强的联系。牙齿脱落反映了牙周炎等口腔疾病的末期状况。已知具有特定牙周病原体的感染是影响CVD发展的可能性因素。本研究的目的是评估CVD患者剩余牙数量与全身炎症状况之间的关系。

我们根据剩余牙数将364例CVD患者分为四组:(i)≥20颗牙齿; (ii)10-19颗牙齿; (iii)1-9颗牙齿;和(iv)无牙颌。记录患者病史,血液数据和牙周状况。获得血清样本并测量其针对三种主要牙周病原体的IgG滴度。

结果:吸烟率和糖尿病的患病率在无牙颌患者和牙齿少的患者中高于剩余多的患者。 1-9牙患者的C反应蛋白水平高于10-19牙和≥20牙的患者。 10?19颗牙齿中牙龈卟啉单胞菌IgG水平高于≥20颗牙齿组中牙龈卟啉单胞菌IgG水平。无牙颌组牙龈卟啉单胞菌IgG水平往往低于其他组。

结论:1-9颗牙齿患者中C反应蛋白水平最高,10-19颗牙齿牙周细菌IgG水平最高。所以,剩余牙齿的数量可用于评估CVD患者全身炎症的严重程度。

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    2018-12-30 feather89
  4. 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    2018-04-06 青山颖钰

    学习了

    0

  5. 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beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=29699, encryptionId=3b0329699d3, topicName=全身炎症)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4f6210986148, createdName=12498dd9m14暂无昵称, createdTime=Thu Apr 05 14:34:00 CST 2018, time=2018-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450854, encodeId=c0a314508540f, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab585558129, createdName=liuyong2982, createdTime=Thu Apr 05 14:34:00 CST 2018, time=2018-04-05, status=1, ipAttribution=)]
    2018-04-05 xue8605
  6. 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  7. 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href='/topic/show?id=46a06e5220c' target=_blank style='color:#2F92EE;'>#牙周病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67522, encryptionId=46a06e5220c, topicName=牙周病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1376173, createdName=linagood, createdTime=Thu Apr 05 14:34:00 CST 2018, time=2018-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1430128, encodeId=8b9f1430128ca, content=<a href='/topic/show?id=b58f6e691fc' target=_blank style='color:#2F92EE;'>#牙齿#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67691, encryptionId=b58f6e691fc, topicName=牙齿)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Thu Apr 05 14:34:00 CST 2018, time=2018-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1498399, encodeId=78941498399b5, content=<a href='/topic/show?id=bb6f89e145a' target=_blank style='color:#2F92EE;'>#血管疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89714, encryptionId=bb6f89e145a, topicName=血管疾病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ccb99370406, createdName=andy2090, createdTime=Thu Apr 05 14:34:00 CST 2018, time=2018-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1516559, encodeId=731f1516559a1, content=<a href='/topic/show?id=3b0329699d3' target=_blank style='color:#2F92EE;'>#全身炎症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=29699, encryptionId=3b0329699d3, topicName=全身炎症)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4f6210986148, createdName=12498dd9m14暂无昵称, createdTime=Thu Apr 05 14:34:00 CST 2018, time=2018-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450854, encodeId=c0a314508540f, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab585558129, createdName=liuyong2982, createdTime=Thu Apr 05 14:34:00 CST 2018, time=2018-04-05, status=1, ipAttribution=)]
    2018-04-05 zhouqu_8
  8. 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  9. 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  10. 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