Inflamm Bowel Dis:生理健康与心理健康的联系--伴有IBD者更易发生焦虑症

2015-07-31 sunshine 译 MedSci原创

研究发现,广泛性焦虑症更常见于伴有克罗恩病或溃疡性结肠炎的个体。据多伦多大学研究人员发表于《炎症性肠病 》的一项新的研究表明,伴有炎症性肠道疾病(IBD)——如克罗恩病或溃疡性结肠炎——的个体发生广泛性焦虑症的风险为不伴有IBD的同龄人的两倍。“伴有IBD的患者面对着大量与此疾病相关的慢性身体问题,”由桑德拉•罗特曼在多伦多大学茵文特许社会工作学院授予职位的Esme Fuller-Tho


研究发现,广泛性焦虑症更常见于伴有克罗恩病或溃疡性结肠炎的个体。据多伦多大学研究人员发表于《炎症性肠病 》的一项新的研究表明,伴有炎症性肠道疾病(IBD)——如克罗恩病或溃疡性结肠炎——的个体发生广泛性焦虑症的风险为不伴有IBD的同龄人的两倍。

“伴有IBD的患者面对着大量与此疾病相关的慢性身体问题,”由桑德拉•罗特曼在多伦多大学茵文特许社会工作学院授予职位的Esme Fuller-Thomson教授,本文的第一作者说道,“焦虑症所带来的负担使得患者的生活更具有挑战性,因此必须解决此‘双重危险’。”

研究人员报道,女性IBD尤其易患焦虑症,伴IBD女性发生焦虑症的风险为伴IBD男性的4倍。
该研究数据来源于2012年加拿大社区健康研究:心理健康,包含了22000余名具有代表性的加拿大人。共269名研究对象患有克罗恩病或溃疡性结肠炎。

“该研究关注于对焦虑症的常规筛查的必要性及有针对性的干预治疗措施,”共同作者及客座讲师 Joanne Sulman说道,“尤其是对于最易发生焦虑症的IBD患者:女性,处于慢性疼痛时期或童年经历过性虐待的女性。”

共同作者 Rusan Lateef指出,对伴有IBD的患者存在两个与焦虑症相关的因素。“特别让人感兴趣的是,童年时期曾有性虐待经历的伴IBD患者发生焦虑症的风险为不伴有此经历的IBD患者的6倍。同样,我们还发现,与不伴有慢性疼痛或仅伴有轻度慢性疼痛的患者相比,患有中/重度慢性疼痛的患者发生焦虑症的风险为其2倍。”

Patrick McGowan,多伦多大学士嘉堡分校的生物科学助理教授,说道,本研究之所以如此重要其中一个原因是,它强调了生理健康与心理健康之间的重要联系。

“我们有时会认为生理和心理是两个完全独立的部分,但实际上二者密不可分,”McGowan说道,“二者均涉及了身体的变化,而且相互影响。”

McGowan指出,尽管本研究没有设计确定焦虑症或炎症性肠道疾病的生物学机制,但是不良的生活习惯及慢性焦虑可威胁到机体的应激系统,影响整个机体的身体过程,包括慢性炎症。
“本研究提出了这些过程之间关联的问题,所以我们并不知道因果关系,但是如果治疗方案较身体或心理健康更广泛,那么这些治疗方案可能会扩大。”

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    2016-01-01 yuandd
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    2016-04-20 lxg951
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    2016-05-17 cmj8wellington
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    2015-08-05 hlycom3356

    不过为科学做出了卓越贡献

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1977413, encodeId=310819e74138b, content=<a href='/topic/show?id=57613630b9' target=_blank style='color:#2F92EE;'>#Bow#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3630, encryptionId=57613630b9, topicName=Bow)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=583c133, createdName=yuandd, createdTime=Fri Jan 01 19:00:00 CST 2016, time=2016-01-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2057576, encodeId=7880205e576b9, content=<a href='/topic/show?id=c02b106e29a' target=_blank style='color:#2F92EE;'>#LAM#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10672, encryptionId=c02b106e29a, topicName=LAM)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=04ce158, createdName=lxg951, createdTime=Wed Apr 20 21:00:00 CST 2016, time=2016-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2011999, encodeId=2105201199996, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Tue May 17 08:00:00 CST 2016, time=2016-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=34431, encodeId=042f3443167, content=不过为科学做出了卓越贡献, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=332823945, createdName=hlycom3356, createdTime=Wed Aug 05 10:13:00 CST 2015, time=2015-08-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=34430, encodeId=c48a3443007, content=这篇文章内容有待参考, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=332823945, createdName=hlycom3356, createdTime=Wed Aug 05 10:12:00 CST 2015, time=2015-08-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=34232, encodeId=82d2342321a, content=好文, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4b531630898, createdName=pine007, createdTime=Mon Aug 03 11:57:00 CST 2015, time=2015-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=34231, encodeId=e22034231ed, content=好文, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4b531630898, createdName=pine007, createdTime=Mon Aug 03 11:57:00 CST 2015, time=2015-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=34230, encodeId=8c8e3423015, content=好文, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4b531630898, createdName=pine007, createdTime=Mon Aug 03 11:57:00 CST 2015, time=2015-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=34229, encodeId=60513422935, content=好文, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4b531630898, createdName=pine007, createdTime=Mon Aug 03 11:57:00 CST 2015, time=2015-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=34228, encodeId=9cb234228c8, content=好文, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4b531630898, createdName=pine007, createdTime=Mon Aug 03 11:57:00 CST 2015, time=2015-08-03, status=1, ipAttribution=)]
    2015-08-05 hlycom3356

    这篇文章内容有待参考

    0

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    2015-08-03 pine007

    好文

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1977413, encodeId=310819e74138b, content=<a href='/topic/show?id=57613630b9' target=_blank style='color:#2F92EE;'>#Bow#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3630, encryptionId=57613630b9, topicName=Bow)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=583c133, createdName=yuandd, createdTime=Fri Jan 01 19:00:00 CST 2016, time=2016-01-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2057576, encodeId=7880205e576b9, content=<a href='/topic/show?id=c02b106e29a' target=_blank style='color:#2F92EE;'>#LAM#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10672, encryptionId=c02b106e29a, topicName=LAM)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=04ce158, createdName=lxg951, createdTime=Wed Apr 20 21:00:00 CST 2016, time=2016-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2011999, encodeId=2105201199996, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Tue May 17 08:00:00 CST 2016, time=2016-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=34431, encodeId=042f3443167, content=不过为科学做出了卓越贡献, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=332823945, createdName=hlycom3356, createdTime=Wed Aug 05 10:13:00 CST 2015, time=2015-08-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=34430, encodeId=c48a3443007, content=这篇文章内容有待参考, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=332823945, createdName=hlycom3356, createdTime=Wed Aug 05 10:12:00 CST 2015, time=2015-08-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=34232, encodeId=82d2342321a, content=好文, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4b531630898, createdName=pine007, createdTime=Mon Aug 03 11:57:00 CST 2015, time=2015-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=34231, encodeId=e22034231ed, content=好文, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4b531630898, createdName=pine007, createdTime=Mon Aug 03 11:57:00 CST 2015, time=2015-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=34230, encodeId=8c8e3423015, content=好文, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4b531630898, createdName=pine007, createdTime=Mon Aug 03 11:57:00 CST 2015, time=2015-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=34229, encodeId=60513422935, content=好文, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4b531630898, createdName=pine007, createdTime=Mon Aug 03 11:57:00 CST 2015, time=2015-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=34228, encodeId=9cb234228c8, content=好文, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4b531630898, createdName=pine007, createdTime=Mon Aug 03 11:57:00 CST 2015, time=2015-08-03, status=1, ipAttribution=)]
    2015-08-03 pine007

    好文

    0

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    2015-08-03 pine007

    好文

    0

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    2015-08-03 pine007

    好文

    0

  10. [GetPortalCommentsPageByObjectIdResponse(id=1977413, encodeId=310819e74138b, content=<a href='/topic/show?id=57613630b9' target=_blank style='color:#2F92EE;'>#Bow#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3630, encryptionId=57613630b9, topicName=Bow)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=583c133, createdName=yuandd, createdTime=Fri Jan 01 19:00:00 CST 2016, time=2016-01-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2057576, encodeId=7880205e576b9, content=<a href='/topic/show?id=c02b106e29a' target=_blank style='color:#2F92EE;'>#LAM#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10672, encryptionId=c02b106e29a, topicName=LAM)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=04ce158, createdName=lxg951, createdTime=Wed Apr 20 21:00:00 CST 2016, time=2016-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2011999, encodeId=2105201199996, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Tue May 17 08:00:00 CST 2016, time=2016-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=34431, encodeId=042f3443167, content=不过为科学做出了卓越贡献, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=332823945, createdName=hlycom3356, createdTime=Wed Aug 05 10:13:00 CST 2015, time=2015-08-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=34430, encodeId=c48a3443007, content=这篇文章内容有待参考, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=332823945, createdName=hlycom3356, createdTime=Wed Aug 05 10:12:00 CST 2015, time=2015-08-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=34232, encodeId=82d2342321a, content=好文, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4b531630898, createdName=pine007, createdTime=Mon Aug 03 11:57:00 CST 2015, time=2015-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=34231, encodeId=e22034231ed, content=好文, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4b531630898, createdName=pine007, createdTime=Mon Aug 03 11:57:00 CST 2015, time=2015-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=34230, encodeId=8c8e3423015, content=好文, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4b531630898, createdName=pine007, createdTime=Mon Aug 03 11:57:00 CST 2015, time=2015-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=34229, encodeId=60513422935, content=好文, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4b531630898, createdName=pine007, createdTime=Mon Aug 03 11:57:00 CST 2015, time=2015-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=34228, encodeId=9cb234228c8, content=好文, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4b531630898, createdName=pine007, createdTime=Mon Aug 03 11:57:00 CST 2015, time=2015-08-03, status=1, ipAttribution=)]
    2015-08-03 pine007

    好文

    0