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Sci Rep：基于脉冲调制AML光纤激光器的人体视网膜成像系统新方法

2019-01-17 MedSci MedSci原创

脉冲调制AML光纤人体视网膜成像系统新方法
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韩国光州科学技术研究院先进光子学研究所的Lee HD和韩国大学医学院眼科的Lee B等人近日在Sci Rep杂志上发表了一篇重要的研究论文，在这项研究中，他们将1080nm波长的脉冲调制AML光纤激光器作为OCT系统的动态扫描源，用于人体视网膜体内成像。

韩国光州科学技术研究院先进光子学研究所的Lee HD和韩国大学医学院眼科的Lee B等人近日在Sci Rep杂志上发表了一篇重要的研究论文，在这项研究中，他们将1080nm波长的脉冲调制AML光纤激光器作为OCT系统的动态扫描源，用于人体视网膜体内成像。

光学相干断层扫描（OCT）是一种非侵入性的成像模式，可以提供组织的高分辨率横截面图像。特别是在视网膜成像中，OCT已成为诊断眼病的更有价值的成像工具之一。考虑到眼睛的散射和吸收等特性，首先选择1000nm OCT系统用于视网膜成像。

动态AML波长扫描光纤激光器采用偏光纤构成，无需缓冲方法，平均线宽为0.625nm，光谱带宽为81.15nm，占空比为90％。他们使用所提出的OCT系统成功地获得了人类视网膜体内图像，没有额外的k时钟，同时可以提供43.1°的宽视场影像。使用该OCT系统，可以将主视网膜层（例如视网膜色素上皮）与OCT图像区分开，轴向分辨率为6.3μm。

原文出处：

Lee， H.D.， et al.， Akinetic swept-source optical coherence tomography based on a pulse-modulated active mode locking fiber laser for human retinal imaging. Sci Rep， 2018. 8(1)： p. 17660.

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    2019-01-28 kord1982

    #新方法#

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=1903355, encodeId=2806190335580, content=<a href='/topic/show?id=e1b0583884b' target=_blank style='color:#2F92EE;'>#新方法#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58388, encryptionId=e1b0583884b, topicName=新方法)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c22f171, createdName=kord1982, createdTime=Mon Jan 28 12:51:00 CST 2019, time=2019-01-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1270160, encodeId=f03812e016014, content=<a href='/topic/show?id=979690e33bd' target=_blank style='color:#2F92EE;'>#视网膜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=90733, encryptionId=979690e33bd, topicName=视网膜)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=742793, createdName=zutt, createdTime=Sat Jan 19 12:51:00 CST 2019, time=2019-01-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1279736, encodeId=de3612e97365e, content=<a href='/topic/show?id=265c66e50ea' target=_blank style='color:#2F92EE;'>#激光#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66750, encryptionId=265c66e50ea, topicName=激光)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4fd6156, createdName=oliver169, createdTime=Sat Jan 19 12:51:00 CST 2019, time=2019-01-19, status=1, ipAttribution=)]
    2019-01-19 zutt

    #视网膜#

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1903355, encodeId=2806190335580, content=<a href='/topic/show?id=e1b0583884b' target=_blank style='color:#2F92EE;'>#新方法#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58388, encryptionId=e1b0583884b, topicName=新方法)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c22f171, createdName=kord1982, createdTime=Mon Jan 28 12:51:00 CST 2019, time=2019-01-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1270160, encodeId=f03812e016014, content=<a href='/topic/show?id=979690e33bd' target=_blank style='color:#2F92EE;'>#视网膜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=90733, encryptionId=979690e33bd, topicName=视网膜)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=742793, createdName=zutt, createdTime=Sat Jan 19 12:51:00 CST 2019, time=2019-01-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1279736, encodeId=de3612e97365e, content=<a href='/topic/show?id=265c66e50ea' target=_blank style='color:#2F92EE;'>#激光#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66750, encryptionId=265c66e50ea, topicName=激光)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4fd6156, createdName=oliver169, createdTime=Sat Jan 19 12:51:00 CST 2019, time=2019-01-19, status=1, ipAttribution=)]
    2019-01-19 oliver169

    #激光#

    0