Chest:结核病合并糖尿病的流行病学和临床管理

2017-04-25 MedSci MedSci原创

目前,研究者们对2型糖尿病(DM)和结核病(TB)之间的相互作用越来越感兴趣,但许多研究问题仍然没有得到解决。流行病学家、基础科学家和临床专家最近召集并确定了优先事项。近期,有关流行病学、临床管理和公共卫生优先研究领域的相关认识发表在杂志Chest上。首先,从流行病学的角度来看,需要更多的研究来确定结核病患者发生暂时性高血糖的重要性,以及DM对全球多药耐药(MDR)-TB流行的重要性。第二,关于合

目前,研究者们对2型糖尿病(DM)和结核病(TB)之间的相互作用越来越感兴趣,但许多研究问题仍然没有得到解决。


流行病学家、基础科学家和临床专家最近召集并确定了优先事项。近期,有关流行病学、临床管理和公共卫生优先研究领域的相关认识发表在杂志Chest上。

首先,从流行病学的角度来看,需要更多的研究来确定结核病患者发生暂时性高血糖的重要性,以及DM对全球多药耐药(MDR)-TB流行的重要性。

第二,关于合并TB-DM疾病的筛查和临床管理,临床试验和大型队列研究应评估改善DM以及TB长期或加强治疗后对TB-DM结局的好处,同时还应调查在新诊断的结核病患者中筛查DM方法的成本效益。

第三,从公共卫生和卫生系统的角度来看,应该考察在高负担人群中,对DM和TB的不同干预措施对人群健康影响和成本效益;同时应该制定卫生系统干预措施以便进行DM筛查、TB治疗完成后管理DM,以及更好地获得全球性的DM服务。鉴于代谢紊、炎症反应、药物和获得保健的异质性,需要对不同种族和环境进行研究。

最后,由于撒哈拉以南非洲和世界其他地区的流行病趋同,应该解决结核病、糖尿病和艾滋病毒之间的相互作用。

原始出处:
Critchley JA, Restrepo BI, et al. Defining a research agenda to address the converging epidemics of tuberculosis and diabetes. Part 1: Epidemiology and clinical management. Chest. 2017 Apr 19. pii: S0012-3692(17)30730-4. doi: 10.1016/j.chest.2017.04.155.  

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    2017-08-10 Smile2680
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    2017-05-01 大爰

    学习了,谢谢分享!!

    0

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    2017-04-27 xugumin
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