BMJ:I型糖尿病孕妇血糖水平与后代出生缺陷研究

2018-07-08 zhangfan MedSci原创

研究发现,I型糖尿病孕妇在孕早期需严格控制血糖以降低后代主要心脏缺陷风险

近日研究人员考察了I型糖尿病母亲孕早期糖化血红蛋白(HbA1c)水平与后代主要出生缺陷风险之间的关联。

2458名I型糖尿病产妇及后代参与研究,研究同时招募1159865名无糖尿病产妇及其后代作为对照组。研究的主要终点是HbA1c校正后主要心脏及非心脏出生缺陷。

2458名糖尿病孕妇后代中发生122例心脏缺陷。每1000名非糖尿病孕妇中,后代心脏缺陷患儿为15例,依据HbA1c <6.5%、6.5%至<7.8%、7.8%至<9.1%以及>9.1%进行分组,每1000名I型糖尿病孕妇中,后代心脏缺陷患儿为33例、49例、44例以及101例。糖尿病孕妇后代中发生50例非心脏缺陷。每1000名非糖尿病孕妇后代心脏缺陷患儿18例,依据HbA1c <6.5%、 6.5%至<7.8%、 7.8%至<9.1%以及>9.1%进行分类,每1000名I型糖尿病孕妇后代心脏缺陷患儿22例、19例、17例以及32例。

研究发现,I型糖尿病孕妇在孕早期需严格控制血糖以降低后代主要心脏缺陷风险。

原始出处:


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    2018-07-09 gaoxiaoe
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    2018-07-08 1ddf0692m34(暂无匿称)

    学习了.长知识

    0

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    2018-07-08 神功盖世

    0

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    2018-07-08 1e17414fm02(暂无匿称)

    学习

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1972042, encodeId=d16919e2042b7, content=<a href='/topic/show?id=c0fc89839ff' target=_blank style='color:#2F92EE;'>#血糖水平#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89839, encryptionId=c0fc89839ff, topicName=血糖水平)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b73f484, createdName=lsj628, createdTime=Wed Jun 19 11:02:00 CST 2019, time=2019-06-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1848556, encodeId=9a7b184855697, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Mon Jul 09 15:02:00 CST 2018, time=2018-07-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=330148, encodeId=57ce3301482d, content=学习了.长知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Sun Jul 08 09:53:38 CST 2018, time=2018-07-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=330140, encodeId=2e2733014095, content=阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/fhZdOu27e88Voqh19n8eF8cLplo8L4nicKtH0WnE3KFELXns5XDu8rsiceK2HHDZc2SEStia5VV3Pia2QLMVqlWbHw/0, createdBy=6e012139475, createdName=神功盖世, createdTime=Sun Jul 08 09:49:14 CST 2018, time=2018-07-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=330129, encodeId=e425330129d6, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfDEeydJz0GlP8O0ngrUX6AYCXFic0XDOOAyeQicIqnOd4TrWSwiagJrsFNYuWC1Uc6iavbS1hWt9xtZAhAqLGHqZyl/0, createdBy=42891977006, createdName=1e17414fm02(暂无匿称), createdTime=Sun Jul 08 09:20:04 CST 2018, time=2018-07-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=330119, encodeId=cef4330119de, content=学习了感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://q.qlogo.cn/qqapp/1103841572/C20CB8E4EBB36F5B821651C710BCB491/100, createdBy=18de1715848, createdName=lofter, createdTime=Sun Jul 08 08:48:31 CST 2018, time=2018-07-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=330112, encodeId=c5a333011294, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=82311653708, createdName=医者仁心5538, createdTime=Sun Jul 08 08:40:05 CST 2018, time=2018-07-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=330111, encodeId=969533011120, content=优质资源.共同学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K0LqDY57Aia0TOQByoJhNt3icm4sfukp500hLH6RHOpFdV01NbECtAV7s0qKpQPibyRukQAwAmqJU3X/0, createdBy=f91f1928792, createdName=九九消寒, createdTime=Sun Jul 08 08:39:47 CST 2018, time=2018-07-08, status=1, ipAttribution=)]
    2018-07-08 lofter

    学习了感谢分享

    0

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    2018-07-08 医者仁心5538

    学习了

    0

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    2018-07-08 九九消寒

    优质资源.共同学习

    0

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