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Diabetic Medicine：尽管有新的药物，2型糖尿病患者严重低血糖发生率有所增加

2017-09-30 MedSci MedSci原创

低血糖
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近日，国际杂志 《Diabetic Medicine》上在线发表一项根据德国健康保险数据进行分析的研究，发现关于尽管有新的药物，2型糖尿病患者严重低血糖发生率有所增加。

近日，国际杂志 《Diabetic Medicine》上在线发表一项根据德国健康保险数据进行分析的研究，发现关于尽管有新的药物，2型糖尿病患者严重低血糖发生率有所增加。通过分析比较2006年和2011年与药物相关的严重低血糖发生率，评估提供有效血糖控制同时降低低血糖风险的新抗高血糖药物的使用。 本研究是一项以人口为基础的研究使用德国医疗保险数据的横断面研究。从被诊断患有2型糖尿病的所有成年人（外推德国人口：2006年为632万人，2011年为752万人）筛查出严重低血糖。通过其解剖治疗化学代码鉴定抗高血糖药物，并计算每种药物的每日剂量。 研究发现2006年严重低血糖事件发生率为每100,000人460例，2011年为每100,000人490例。2006年和2011年，所有严重低血糖人群使用磺脲类治疗分别为10.9％和7.3％，二甲双胍和磺酰脲类联合治疗分别12.7％和9.3％。在严重低血糖症患者中，2006年没有二肽基肽酶-4抑制剂或胰高血糖素样肽-1受体激动剂的处方，但在2011年，严重低血糖患者中有1.55％和0.17％接受了相应的治疗。2006年与2011年相比，人胰岛素引起的严

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    2017-11-03 fmq_28614562

    #严重低血糖#

    0

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    2018-02-18 jeanqiuqiu

    #DIC#

    0

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    2018-06-28 chenzhuanggui

    #Diabetic#

    0

  4. 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createdBy=6f7770, createdName=jeanqiuqiu, createdTime=Sun Feb 18 00:48:00 CST 2018, time=2018-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1970530, encodeId=e55619e05307c, content=<a href='/topic/show?id=fa5d5919df' target=_blank style='color:#2F92EE;'>#Diabetic#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5919, encryptionId=fa5d5919df, topicName=Diabetic)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8949377, createdName=chenzhuanggui, createdTime=Thu Jun 28 08:48:00 CST 2018, time=2018-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1773657, encodeId=7d331e7365797, content=<a href='/topic/show?id=5f014e1852' target=_blank style='color:#2F92EE;'>#CIN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4718, encryptionId=5f014e1852, topicName=CIN)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a9a038523631, createdName=kalseyzl, createdTime=Sat Jul 14 02:48:00 CST 2018, time=2018-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1760233, encodeId=13151e60233a2, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9a1a37427546, createdName=ms5439512287675881, createdTime=Wed Dec 06 22:48:00 CST 2017, time=2017-12-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1748112, encodeId=78e31e48112f4, content=<a href='/topic/show?id=9f672636086' target=_blank style='color:#2F92EE;'>#低血糖发生率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26360, encryptionId=9f672636086, topicName=低血糖发生率)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=aea936056349, createdName=DEXTER3151, createdTime=Fri Jun 08 16:48:00 CST 2018, time=2018-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1826382, encodeId=5bbe1826382d2, content=<a href='/topic/show?id=e5283e89970' target=_blank style='color:#2F92EE;'>#发生率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=19, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37899, encryptionId=e5283e89970, topicName=发生率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=一叶知秋, createdTime=Fri Jun 29 02:48:00 CST 2018, time=2018-06-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1638068, encodeId=0f7a1638068d4, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=17, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Tue May 22 22:48:00 CST 2018, time=2018-05-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1383347, encodeId=017a138334e2b, content=<a href='/topic/show?id=196a1101f7' target=_blank style='color:#2F92EE;'>#2型糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1101, encryptionId=196a1101f7, topicName=2型糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ec19483, createdName=aids213, createdTime=Mon Oct 02 08:48:00 CST 2017, time=2017-10-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1474306, encodeId=774314e4306db, content=<a href='/topic/show?id=935fe6718e3' target=_blank style='color:#2F92EE;'>#糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76718, encryptionId=935fe6718e3, topicName=糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a38f7243741, createdName=xue8604, createdTime=Mon Oct 02 08:48:00 CST 2017, time=2017-10-02, status=1, ipAttribution=)]
    2018-07-14 kalseyzl

    #CIN#

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1685698, encodeId=2c5d168569816, content=<a href='/topic/show?id=f05d21150d1' target=_blank style='color:#2F92EE;'>#严重低血糖#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=21150, encryptionId=f05d21150d1, topicName=严重低血糖)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fc1428252752, createdName=fmq_28614562, createdTime=Fri Nov 03 18:48:00 CST 2017, time=2017-11-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1858789, encodeId=1da01858e893d, content=<a href='/topic/show?id=e0a9593596' target=_blank style='color:#2F92EE;'>#DIC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5935, encryptionId=e0a9593596, topicName=DIC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6f7770, createdName=jeanqiuqiu, createdTime=Sun Feb 18 00:48:00 CST 2018, time=2018-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1970530, encodeId=e55619e05307c, content=<a href='/topic/show?id=fa5d5919df' target=_blank style='color:#2F92EE;'>#Diabetic#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5919, encryptionId=fa5d5919df, topicName=Diabetic)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8949377, createdName=chenzhuanggui, createdTime=Thu Jun 28 08:48:00 CST 2018, time=2018-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1773657, encodeId=7d331e7365797, content=<a href='/topic/show?id=5f014e1852' target=_blank style='color:#2F92EE;'>#CIN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, 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style='color:#2F92EE;'>#低血糖发生率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26360, encryptionId=9f672636086, topicName=低血糖发生率)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=aea936056349, createdName=DEXTER3151, createdTime=Fri Jun 08 16:48:00 CST 2018, time=2018-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1826382, encodeId=5bbe1826382d2, content=<a href='/topic/show?id=e5283e89970' target=_blank style='color:#2F92EE;'>#发生率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=19, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37899, encryptionId=e5283e89970, topicName=发生率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=一叶知秋, createdTime=Fri Jun 29 02:48:00 CST 2018, time=2018-06-29, status=1, ipAttribution=), 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createdBy=ec19483, createdName=aids213, createdTime=Mon Oct 02 08:48:00 CST 2017, time=2017-10-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1474306, encodeId=774314e4306db, content=<a href='/topic/show?id=935fe6718e3' target=_blank style='color:#2F92EE;'>#糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76718, encryptionId=935fe6718e3, topicName=糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a38f7243741, createdName=xue8604, createdTime=Mon Oct 02 08:48:00 CST 2017, time=2017-10-02, status=1, ipAttribution=)]
    2017-12-06 ms5439512287675881

    #BET#

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1685698, encodeId=2c5d168569816, content=<a href='/topic/show?id=f05d21150d1' target=_blank style='color:#2F92EE;'>#严重低血糖#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=21150, encryptionId=f05d21150d1, topicName=严重低血糖)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fc1428252752, createdName=fmq_28614562, createdTime=Fri Nov 03 18:48:00 CST 2017, time=2017-11-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1858789, encodeId=1da01858e893d, content=<a href='/topic/show?id=e0a9593596' target=_blank style='color:#2F92EE;'>#DIC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5935, encryptionId=e0a9593596, topicName=DIC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6f7770, createdName=jeanqiuqiu, createdTime=Sun Feb 18 00:48:00 CST 2018, time=2018-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1970530, encodeId=e55619e05307c, content=<a href='/topic/show?id=fa5d5919df' target=_blank style='color:#2F92EE;'>#Diabetic#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5919, encryptionId=fa5d5919df, topicName=Diabetic)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8949377, createdName=chenzhuanggui, createdTime=Thu Jun 28 08:48:00 CST 2018, time=2018-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1773657, encodeId=7d331e7365797, content=<a href='/topic/show?id=5f014e1852' target=_blank style='color:#2F92EE;'>#CIN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, 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style='color:#2F92EE;'>#低血糖发生率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26360, encryptionId=9f672636086, topicName=低血糖发生率)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=aea936056349, createdName=DEXTER3151, createdTime=Fri Jun 08 16:48:00 CST 2018, time=2018-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1826382, encodeId=5bbe1826382d2, content=<a href='/topic/show?id=e5283e89970' target=_blank style='color:#2F92EE;'>#发生率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=19, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37899, encryptionId=e5283e89970, topicName=发生率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=一叶知秋, createdTime=Fri Jun 29 02:48:00 CST 2018, time=2018-06-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1638068, encodeId=0f7a1638068d4, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=17, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Tue May 22 22:48:00 CST 2018, time=2018-05-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1383347, encodeId=017a138334e2b, content=<a href='/topic/show?id=196a1101f7' target=_blank style='color:#2F92EE;'>#2型糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1101, encryptionId=196a1101f7, topicName=2型糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ec19483, createdName=aids213, createdTime=Mon Oct 02 08:48:00 CST 2017, time=2017-10-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1474306, encodeId=774314e4306db, content=<a href='/topic/show?id=935fe6718e3' target=_blank style='color:#2F92EE;'>#糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76718, encryptionId=935fe6718e3, topicName=糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a38f7243741, createdName=xue8604, createdTime=Mon Oct 02 08:48:00 CST 2017, time=2017-10-02, status=1, ipAttribution=)]
    2018-06-08 DEXTER3151

    #低血糖发生率#

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1685698, encodeId=2c5d168569816, content=<a href='/topic/show?id=f05d21150d1' target=_blank style='color:#2F92EE;'>#严重低血糖#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=21150, encryptionId=f05d21150d1, topicName=严重低血糖)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fc1428252752, createdName=fmq_28614562, createdTime=Fri Nov 03 18:48:00 CST 2017, time=2017-11-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1858789, encodeId=1da01858e893d, content=<a href='/topic/show?id=e0a9593596' target=_blank style='color:#2F92EE;'>#DIC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5935, encryptionId=e0a9593596, topicName=DIC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6f7770, createdName=jeanqiuqiu, createdTime=Sun Feb 18 00:48:00 CST 2018, time=2018-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1970530, encodeId=e55619e05307c, content=<a href='/topic/show?id=fa5d5919df' target=_blank style='color:#2F92EE;'>#Diabetic#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5919, encryptionId=fa5d5919df, topicName=Diabetic)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8949377, createdName=chenzhuanggui, createdTime=Thu Jun 28 08:48:00 CST 2018, time=2018-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1773657, encodeId=7d331e7365797, content=<a href='/topic/show?id=5f014e1852' target=_blank style='color:#2F92EE;'>#CIN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, 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style='color:#2F92EE;'>#低血糖发生率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26360, encryptionId=9f672636086, topicName=低血糖发生率)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=aea936056349, createdName=DEXTER3151, createdTime=Fri Jun 08 16:48:00 CST 2018, time=2018-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1826382, encodeId=5bbe1826382d2, content=<a href='/topic/show?id=e5283e89970' target=_blank style='color:#2F92EE;'>#发生率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=19, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37899, encryptionId=e5283e89970, topicName=发生率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=一叶知秋, createdTime=Fri Jun 29 02:48:00 CST 2018, time=2018-06-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1638068, encodeId=0f7a1638068d4, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=17, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Tue May 22 22:48:00 CST 2018, time=2018-05-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1383347, encodeId=017a138334e2b, content=<a href='/topic/show?id=196a1101f7' target=_blank style='color:#2F92EE;'>#2型糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1101, encryptionId=196a1101f7, topicName=2型糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ec19483, createdName=aids213, createdTime=Mon Oct 02 08:48:00 CST 2017, time=2017-10-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1474306, encodeId=774314e4306db, content=<a href='/topic/show?id=935fe6718e3' target=_blank style='color:#2F92EE;'>#糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76718, encryptionId=935fe6718e3, topicName=糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a38f7243741, createdName=xue8604, createdTime=Mon Oct 02 08:48:00 CST 2017, time=2017-10-02, status=1, ipAttribution=)]
    2018-06-29 一叶知秋

    #发生率#

    0

  8. 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createdBy=ec19483, createdName=aids213, createdTime=Mon Oct 02 08:48:00 CST 2017, time=2017-10-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1474306, encodeId=774314e4306db, content=<a href='/topic/show?id=935fe6718e3' target=_blank style='color:#2F92EE;'>#糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76718, encryptionId=935fe6718e3, topicName=糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a38f7243741, createdName=xue8604, createdTime=Mon Oct 02 08:48:00 CST 2017, time=2017-10-02, status=1, ipAttribution=)]
    2018-05-22 ms9608593228839890

    #DIA#

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=1685698, encodeId=2c5d168569816, content=<a href='/topic/show?id=f05d21150d1' target=_blank style='color:#2F92EE;'>#严重低血糖#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=21150, encryptionId=f05d21150d1, topicName=严重低血糖)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fc1428252752, createdName=fmq_28614562, createdTime=Fri Nov 03 18:48:00 CST 2017, time=2017-11-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1858789, encodeId=1da01858e893d, content=<a href='/topic/show?id=e0a9593596' target=_blank style='color:#2F92EE;'>#DIC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5935, encryptionId=e0a9593596, topicName=DIC)], attachment=null, authenticateStatus=null, createdAvatar=, 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createdBy=ec19483, createdName=aids213, createdTime=Mon Oct 02 08:48:00 CST 2017, time=2017-10-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1474306, encodeId=774314e4306db, content=<a href='/topic/show?id=935fe6718e3' target=_blank style='color:#2F92EE;'>#糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76718, encryptionId=935fe6718e3, topicName=糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a38f7243741, createdName=xue8604, createdTime=Mon Oct 02 08:48:00 CST 2017, time=2017-10-02, status=1, ipAttribution=)]
    2017-10-02 aids213

    #2型糖尿病患者#

    0

  10. 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    2017-10-02 xue8604

    #糖尿病患者#

    0

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磺脲类药物与心血管不良事件和低血糖的风险增加有关，但目前仍不清楚这些风险是否随不同的药剂而发生变化。近期，一项发表在杂志Diabetes Care上的研究评估了根据胰腺特异性和药物作用持续时间分组的磺脲类药物，其导致的急性心肌梗死、缺血性卒中、心血管死亡、全因死亡率和严重低血糖风险是否不同。此项研究使用英国临床实践研究数据链，与医院数据统计数据和国家统计局数据库相关联，在1998年至2013年期间