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Curr Opin Allergy Clin Immunol：眼睛表面的神经性症状：干燥，疼痛和瘙痒！

2017-09-04 cuiguizhong MedSci原创

眼睛表面神经性症状干燥疼痛瘙痒
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美国迈阿密大学皮肤科和迈阿密痒中心的Andersen HH 近日在Curr Opin Allergy Clin Immunol 发表了一篇文章，系统的描述近期关于眼表的神经性症状在流行病学、病理生理学和临床管理的研究结果，重点是对干眼症的疼痛和瘙痒感之间潜在相似之处进行论述。

美国迈阿密大学皮肤科和迈阿密痒中心的Andersen HH 近日在Curr Opin Allergy Clin Immunol 发表了一篇文章，系统的描述近期关于眼表的神经性症状在流行病学、病理生理学和临床管理的研究结果，重点是对干眼症的疼痛和瘙痒感之间潜在相似之处进行论述。

他们对文献进行研究，包括干眼症相关研究，眼表的神经性症状、眼痛、瘙痒以及瘙痒和疼痛神经生物学方面的参考文献。最近的研究结果表明干眼症、慢性眼痛和瘙痒症状的方面是由神经病理性疼痛机制引起的，这涉及周围和中枢神经系统的致敏过程。

眼部干燥、疼痛和瘙痒是常见的病症，它们之间存在几个共同的特点。在产生和维持这些眼部感觉症状方面，多层次证据表明这和外周和中枢神经元敏化过程相关。同时，作者指出，对于眼睛感觉的流行病学研究、眼睛损害后感觉和瘙痒的分子机制研究，特定背景下眼睛疾病动物模型中的电生理学改变研究，以及减轻不愉快的眼睛感觉治疗方式的研究等仍需要进一步的推进。

原文出处：

Andersen， H.H.， G. Yosipovitch， and A. Galor， Neuropathic symptoms of the ocular surface： dryness， pain， and itch. Curr Opin Allergy Clin Immunol， 2017. 17(5)： p. 373-381.

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    2017-12-12 rebeccajiejie

    #眼睛表面#

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    2017-12-09 hywen7326

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    2017-09-06 listen318

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    2017-09-06 膀胱癌

    #ALL#

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  6. [GetPortalCommentsPageByObjectIdResponse(id=1800692, encodeId=a111180069252, content=<a href='/topic/show?id=8084e284579' target=_blank style='color:#2F92EE;'>#眼睛表面#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72845, encryptionId=8084e284579, topicName=眼睛表面)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e1cc90, createdName=rebeccajiejie, createdTime=Tue Dec 12 21:19:00 CST 2017, time=2017-12-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2035414, encodeId=704f203541447, content=<a href='/topic/show?id=d382e42956d' target=_blank style='color:#2F92EE;'>#神经性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74295, encryptionId=d382e42956d, topicName=神经性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=927d310, createdName=hywen7326, createdTime=Sat Dec 09 20:19:00 CST 2017, time=2017-12-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1801823, encodeId=79ed1801823f2, content=<a href='/topic/show?id=5b24e4307e9' target=_blank style='color:#2F92EE;'>#神经性症状#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74307, encryptionId=5b24e4307e9, topicName=神经性症状)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e9a6357, createdName=xiangyuzhou971, createdTime=Fri Feb 23 19:19:00 CST 2018, time=2018-02-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1302556, encodeId=22b0130255648, content=<a href='/topic/show?id=b541e1219dc' target=_blank style='color:#2F92EE;'>#瘙痒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71219, encryptionId=b541e1219dc, topicName=瘙痒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9d17305, createdName=listen318, createdTime=Wed Sep 06 09:19:00 CST 2017, time=2017-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1329014, encodeId=bc5d13290142d, content=<a href='/topic/show?id=bb96232801' target=_blank style='color:#2F92EE;'>#ALL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2328, encryptionId=bb96232801, topicName=ALL)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/C2EFD5CFB07FE291138AD4FD0C98E3DE/100, createdBy=e3d52500031, createdName=膀胱癌, createdTime=Wed Sep 06 09:19:00 CST 2017, time=2017-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=240438, encodeId=cdfe24043888, content=学习了.涨知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Mon Sep 04 18:44:03 CST 2017, time=2017-09-04, status=1, ipAttribution=)]
    2017-09-04 1ddf0692m34(暂无匿称)

    学习了.涨知识

    0