J Periodontol:吸烟者慢性牙周炎应激、血清和唾液中皮质醇及白细胞介素-1β的水平

2018-09-25 MedSci MedSci原创

有文献表明,压力与慢性牙周炎(CP)之间存在正相关关系,但关于压力和吸烟对牙周病进展的综合影响的信息有限。因此,本研究的目的是评估CP吸烟者的压力,唾液和血清皮质醇和白细胞介素-1β水平的影响。

有文献表明,压力与慢性牙周炎(CP)之间存在正相关关系,但关于压力和吸烟对牙周病进展的综合影响的信息有限。因此,本研究的目的是评估CP吸烟者的压力,唾液和血清皮质醇和白细胞介素-1β水平的影响。

方法:75名患者平均分为三组,健康对照组(I组),吸烟者和非吸烟者CP组(组2和组3)。通过酶联免疫吸附试验(ELISA)评估唾液和血清皮质醇的生化参数和IL-1β水平。使用 Zung的自评抑郁量表问卷确定患者的压力水平。

结果:与不吸烟者相比,CP吸烟者的牙周袋探诊深度,临床附着水平,菌斑指数较高;龈乳头出血指数和牙龈指数得分均较低。与组3的血清值相比,第2组的唾液皮质醇和IL-1β相对较高。与第3组患者相比,第2组患者抑郁评分较高。第2组患者的抑郁评分与唾液皮质醇呈显着正相关。

结果表明,患有CP的吸烟者血清和唾液皮质醇,IL-1β和应激水平显着更高,因此他们可能表现出更高的风险和牙周病严重程度。需要进一步研究牙周炎与压力之间的关系。

原始出处:

Pranjali V. Bawankar, et al.Evaluation of stress, serum and salivary cortisol, and interleukin‐1β levels in smokers and non‐smokers with chronic periodontitis. Journal of  Periodontology. 2018 September. Doi:10.1002/JPER.18-0028

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    2019-01-25 feather89
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