CHEST:慢性阻塞性肺疾病患者,记得测测你的骨密度哦!

2016-12-27 MedSci MedSci原创

肌肉减少症和骨质疏松症是慢性阻塞性肺病(COPD)的全身特征。近期,一项发表在CHEST杂志上的文章研究了肌肉减少症和骨质减少/骨质疏松症之间的关联,以及在男性COPD患者中与骨密度(BMD)降低的相关因素。此项研究选取了2008年至2011年韩国国家健康和营养检查调查数据库中的777名接受了肺功能测试和双能X线吸收测定法的男性COPD患者的数据。四肢的骨量质指数(ASMI)评估肌肉减少情况,T评

肌肉减少症和骨质疏松症是慢性阻塞性肺病(COPD)的全身特征。

近期,一项发表在CHEST杂志上的文章研究了肌肉减少症和骨质减少/骨质疏松症之间的关联,以及在男性COPD患者中与骨密度(BMD)降低的相关因素。

此项研究选取了2008年至2011年韩国国家健康和营养检查调查数据库中的777名接受了肺功能测试和双能X线吸收测定法的男性COPD患者的数据。四肢的骨量质指数(ASMI)评估肌肉减少情况,T评分评估骨质减少/骨质疏松情况。

此项研究结果显示:随着气流受限的严重性增加,肌肉减少症患病率增加(Ptrend<0.001)。此外,随着骨骼肌减少程度的加重,骨质减少/骨质疏松症患病率增加(Ptrend<0.001),并且在四肢骨骼肌质量和骨密度之间存在显着的正相关(ASMI-T评分:r=0.408,P<0.001)。男性COPD患者中,肌肉减少症与低骨密度的风险增加相关(OR=2.31;95%CI,1.53-3.46;P<0.001)。

在肌肉减少症及非肌肉减少症受调查者中,高龄和低脂肪量与低骨密度显着相关。在肌肉骨骼减少症受调查者中,高血清血红蛋白和胰岛素水平与低骨密度的风险降低相关,而运动和饮食摄入量与低骨密度风险的相关性仅在非肌肉骨骼减少症的受调查者发现。

此项研究得出结论:在男性COPD患者中,肌肉减少症与骨质减少/骨质疏松症密切相关。此外,根据该群体中是否存在肌肉减少症,不同的因素与低BMD相关。

原始出处:
Hwang JA, Kim YS, Leem AY, Park MS, Kim SK, Chang J, Jung JY. Clinical implications of sarcopenia on decreased bone density in men with chronic obstructive pulmonary disease. Chest. 2016 Dec 21. pii: S0012-3692(16)62596-5. doi:10.1016/j.chest.2016.12.006.

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    2017-07-23 Smile2680
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    2017-08-23 tomyang96
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    2017-01-03 虈亣靌

    很好,不错,以后会多学习

    0

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    2016-12-28 aleale

    真的吗?

    0

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    2016-12-28 1e10c84am36(暂无匿称)

    文章好好

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1929266, encodeId=9c8d192926610, content=<a href='/topic/show?id=9e604625ab' target=_blank style='color:#2F92EE;'>#Chest#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4625, encryptionId=9e604625ab, topicName=Chest)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c48a270, createdName=Smile2680, createdTime=Sun Jul 23 09:52:00 CST 2017, time=2017-07-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1696694, encodeId=0c64169669404, content=<a href='/topic/show?id=d2e99e651e4' target=_blank style='color:#2F92EE;'>#阻塞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97651, encryptionId=d2e99e651e4, topicName=阻塞)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a23129903429, createdName=tomyang96, createdTime=Wed Aug 23 03:52:00 CST 2017, time=2017-08-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1798969, encodeId=92ce1e989697a, content=<a href='/topic/show?id=38e0e0670ff' target=_blank style='color:#2F92EE;'>#疾病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70670, encryptionId=38e0e0670ff, topicName=疾病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c859411, createdName=hmwwww, createdTime=Tue Sep 05 00:52:00 CST 2017, time=2017-09-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=167740, encodeId=464b16e740bb, content=很好,不错,以后会多学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Tue Jan 03 19:27:41 CST 2017, time=2017-01-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2050577, encodeId=713220505e7e4, content=<a href='/topic/show?id=95f8e042dd' target=_blank style='color:#2F92EE;'>#EST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7042, encryptionId=95f8e042dd, topicName=EST)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e9a6357, createdName=xiangyuzhou971, createdTime=Sat Sep 09 04:52:00 CST 2017, time=2017-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=166337, encodeId=1de016633e04, content=真的吗?, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKVkILniabnuT4anP3RF0Vej3wtdQkUBaoVQQnEtgRJuCA6d08SVmHylJsibr3ZOX3icakISxC61l5Aw/132, createdBy=bd3e1976218, createdName=aleale, createdTime=Wed Dec 28 13:04:21 CST 2016, time=2016-12-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=166270, encodeId=063e1662e053, content=文章好好, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Wed Dec 28 09:00:30 CST 2016, time=2016-12-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=166167, encodeId=d4f216616eba, content=棒棒哒?????????, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=76491981781, createdName=1e184d7bm65(暂无匿称), createdTime=Tue Dec 27 22:50:22 CST 2016, time=2016-12-27, status=1, ipAttribution=)]
    2016-12-27 1e184d7bm65(暂无匿称)

    棒棒哒?????????

    0

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