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Rheumatol Int：治疗贝切特氏病相关葡萄膜炎的生物疗法综述！

2017-07-30 cuiguizhong MedSci原创

眼内炎贝切特氏病生物治疗
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意大利锡耶纳大学风湿病眼科协作葡萄膜炎中心的Sota J近日在Korean J Ophthalmol 发表了一篇综述，系统的阐述了眼内炎治疗药物的现状，也指出其他可能的潜在治疗药物。

意大利锡耶纳大学风湿病眼科协作葡萄膜炎中心的Sota J近日在Korean J Ophthalmol 发表了一篇综述，系统的阐述了眼内炎治疗药物的现状，也指出其他可能的潜在治疗药物。

眼内炎症是贝切特氏病（Behcet's disease，BD）相关的并发症之一，往往对药物反应不佳。包括坏死性白血球闭塞性脉管炎在内的眼组织病理学变化与其他器官中发生的组织病理学变化基本类似，可能是由于免疫复合物介导的，同时可以影响所有大小的动脉和静脉。

越来越多的研究表明，在对贝切特氏病的治疗中，除了抗肿瘤坏死因子（TNF）-α药物以外，其他的生物制剂，包括白细胞介素-1和白细胞介素-6阻断剂， 西布单抗，乌斯卡单抗，达替珠单抗，利妥昔单抗和安非他明等药物也具有潜在作用。作者在发表的综述中进行了详细的论述。但同时，作者也指出，对于难治性的贝切特氏病，仍需要大量的研究来充分阐明和确定这些不同药物的临床疗效。

原文出处：


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    2017-12-30 124984edm32暂无昵称

    #生物疗法#

    0

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    2017-08-01 大爰

    学习了谢谢分享！！

    0

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    2017-07-31 1e0e5a1fm42(暂无匿称)

    henhao

    0

  4. 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createdTime=Tue Aug 01 07:46:22 CST 2017, time=2017-08-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=228384, encodeId=605422838448, content=henhao, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NcXNhUvfhzd2VdicMnaLeK2Im5gKx4Ucxd8Bwu6S7RG0uILBFQx5HTW2bU4VricDYlQqN20ibASSMYAeGrZrrTpy2Q/0, createdBy=7dcf1938111, createdName=1e0e5a1fm42(暂无匿称), createdTime=Mon Jul 31 09:08:09 CST 2017, time=2017-07-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=228364, encodeId=763a228364f2, content=学习，谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyhb9xDeHojCicsdRdyC3XXdGk2ib9yLypZuHN06WeW4HO8WN0GGrgEfvnTX8gsckof05GHOU5OM4Mvx/0, createdBy=9cee1982656, createdName=执着追梦, createdTime=Mon Jul 31 08:34:37 CST 2017, time=2017-07-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=228329, encodeId=24012283291a, content=学习了谢谢分享！！, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Mon Jul 31 07:40:30 CST 2017, time=2017-07-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=228272, encodeId=52e32282e234, content=不错的，学习了，谢谢分享！, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, 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channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo5nmIH5IQqCKjJgSCuicPWUWOUcdqt1ROPnEiaOYN4pSHibDv8la3OxNLalvuvUXn8clpJlrpuyTpckgt9OPkeSSdT/0, createdBy=8fd71930726, createdName=半夏微凉, createdTime=Mon Jul 31 05:49:04 CST 2017, time=2017-07-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=228235, encodeId=aa75228235f3, content=学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzR8ylhYfiaoAUx2BsaYHVia1IKhG3Cg8CT84rBrn6iaVRkyAibJxBcLEXabOQ5p19vWgDe34ib5ErxNgx/0, createdBy=8a701629084, createdName=jihuaijun1112, createdTime=Mon Jul 31 00:29:37 CST 2017, time=2017-07-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=228215, encodeId=e5c4228215eb, content=学习学习，谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuBA90ng5ibXMmibn1feGOQ2cjw0S48DKsF0icicFlmRxwHibIic2TNGd22vVqkKRMj2cRSWbpqZAPBPgdt/0, createdBy=81031668757, createdName=林3301, createdTime=Sun Jul 30 23:51:57 CST 2017, time=2017-07-30, status=1, ipAttribution=)]
    2017-07-31 执着追梦

    学习，谢谢分享

    0

  5. 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    2017-07-31 大爰

    学习了谢谢分享！！

    0

  6. 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    2017-07-31 中医痴

    不错的，学习了，谢谢分享！

    0

  7. 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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NdqKgfW3nMpOkC3jXxiaW2po0PtglY5ZuVjERqKADW4HyMI8bcZXWlKgH7tEP9ULBoBzuQMibia4pr1s9rQPqLvqQJ/0, createdBy=e8c02060444, createdName=中医痴, createdTime=Mon Jul 31 06:06:57 CST 2017, time=2017-07-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=228259, encodeId=6ece2282594a, content=值得推荐一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLBWOEtiahpXHGVdbFId5PLgK775YNA1ria3lM9KsJT6iczgIhov5sobd1Nr0raUBP58GkUDzvfDic9RCg/0, createdBy=0d021989245, createdName=189****1577, createdTime=Mon Jul 31 05:52:49 CST 2017, time=2017-07-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=228254, encodeId=d9b8228254c3, content=阅读了谢谢分享, beContent=null, objectType=article, 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    2017-07-31 189****1577

    值得推荐一下

    0

  8. 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    2017-07-31 半夏微凉

    阅读了谢谢分享

    0

  9. 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    2017-07-31 jihuaijun1112

    学习学习学习

    0

  10. 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    2017-07-30 林3301

    学习学习，谢谢分享

    0

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