ACOG实践指南:雌激素依赖性乳腺癌史的病人中阴道雌激素的使用

2016-02-24 MedSci MedSci原创

AOCG实践指南第659号:在有雌激素依赖性乳腺癌病史的女性中阴道雌激素的使用 摘要:癌症治疗应关注特殊女性人群的生存问题,包括癌症导致的高雌激素相关的副反应和癌症幸存者自然绝经后的不良反应。全身性和阴道雌激素广泛用于缓解血管舒缩,性交障碍,和一般人群下尿路感染等相关症状。然而,考虑到部分癌症是雌激素敏感的,对目前患有乳腺癌或曾有乳腺癌病史的女性使用激素疗法的安全性仍令人担忧。 建议和

AOCG实践指南第659号:在有雌激素依赖性乳腺癌病史的女性中阴道雌激素的使用

摘要:癌症治疗应关注特殊女性人群的生存问题,包括癌症导致的高雌激素相关的副反应和癌症幸存者自然绝经后的不良反应。全身性和阴道雌激素广泛用于缓解血管舒缩,性交障碍,和一般人群下尿路感染等相关症状。然而,考虑到部分癌症是雌激素敏感的,对目前患有乳腺癌或曾有乳腺癌病史的女性使用激素疗法的安全性仍令人担忧。

建议和总结:

正在经历乳腺癌和乳腺癌治疗后女性,控制泌尿生殖道症状和萎缩相关的尿路症状的一线治疗是非激素疗法。

雌激素依赖性乳腺癌病史的女性出现泌尿生殖道症状,非激素疗法无效时,可考虑使用阴道雌激素。

使用阴道雌激素应与患者的肿瘤医生协调决定。另外,应以知情同意为前提,在女性获知使用低剂量阴道雌激素的利弊后做出决定。

没有数据显示对正在接受乳腺癌治疗和有乳腺癌病史的女性中使用阴道雌激素缓解泌尿生殖道症状会增加肿瘤复发的风险。

当决定使用阴道雌激素时,应按照能缓解阴道症状的最小剂量和有限时间内使用。

原始出处:





 

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=2030984, encodeId=5e68203098494, content=<a href='/topic/show?id=5df2460e269' target=_blank style='color:#2F92EE;'>#实践指南#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46072, encryptionId=5df2460e269, topicName=实践指南)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=796422, createdName=lvliquan, createdTime=Sun Mar 06 05:51:00 CST 2016, time=2016-03-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1816406, encodeId=458a1816406e8, content=<a href='/topic/show?id=0c649e6170f' target=_blank style='color:#2F92EE;'>#阴道雌激素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97617, encryptionId=0c649e6170f, topicName=阴道雌激素)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3c932500160, createdName=ms7421025882867189, createdTime=Tue Jan 17 05:51:00 CST 2017, time=2017-01-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1991143, encodeId=9d2819911433e, content=<a href='/topic/show?id=316798e58dc' target=_blank style='color:#2F92EE;'>#雌激素依赖性乳腺癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98758, encryptionId=316798e58dc, topicName=雌激素依赖性乳腺癌)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Thu Oct 27 09:51:00 CST 2016, time=2016-10-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=95582, encodeId=3a0d9558248, content=了解一下!, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Tue Aug 02 22:16:00 CST 2016, time=2016-08-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1581214, encodeId=90881581214bb, content=<a href='/topic/show?id=4995186984' target=_blank style='color:#2F92EE;'>#ACOG#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1869, encryptionId=4995186984, topicName=ACOG)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=仁心济世, createdTime=Thu Feb 25 15:51:00 CST 2016, time=2016-02-25, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=2030984, encodeId=5e68203098494, content=<a href='/topic/show?id=5df2460e269' target=_blank style='color:#2F92EE;'>#实践指南#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46072, encryptionId=5df2460e269, topicName=实践指南)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=796422, createdName=lvliquan, createdTime=Sun Mar 06 05:51:00 CST 2016, time=2016-03-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1816406, encodeId=458a1816406e8, content=<a href='/topic/show?id=0c649e6170f' target=_blank style='color:#2F92EE;'>#阴道雌激素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97617, encryptionId=0c649e6170f, topicName=阴道雌激素)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3c932500160, createdName=ms7421025882867189, createdTime=Tue Jan 17 05:51:00 CST 2017, time=2017-01-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1991143, encodeId=9d2819911433e, content=<a href='/topic/show?id=316798e58dc' target=_blank style='color:#2F92EE;'>#雌激素依赖性乳腺癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98758, encryptionId=316798e58dc, topicName=雌激素依赖性乳腺癌)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Thu Oct 27 09:51:00 CST 2016, time=2016-10-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=95582, encodeId=3a0d9558248, content=了解一下!, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Tue Aug 02 22:16:00 CST 2016, time=2016-08-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1581214, encodeId=90881581214bb, content=<a href='/topic/show?id=4995186984' target=_blank style='color:#2F92EE;'>#ACOG#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1869, encryptionId=4995186984, topicName=ACOG)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=仁心济世, createdTime=Thu Feb 25 15:51:00 CST 2016, time=2016-02-25, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=2030984, encodeId=5e68203098494, content=<a href='/topic/show?id=5df2460e269' target=_blank style='color:#2F92EE;'>#实践指南#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46072, encryptionId=5df2460e269, topicName=实践指南)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=796422, createdName=lvliquan, createdTime=Sun Mar 06 05:51:00 CST 2016, time=2016-03-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1816406, encodeId=458a1816406e8, content=<a href='/topic/show?id=0c649e6170f' target=_blank style='color:#2F92EE;'>#阴道雌激素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97617, encryptionId=0c649e6170f, topicName=阴道雌激素)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3c932500160, createdName=ms7421025882867189, createdTime=Tue Jan 17 05:51:00 CST 2017, time=2017-01-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1991143, encodeId=9d2819911433e, content=<a href='/topic/show?id=316798e58dc' target=_blank style='color:#2F92EE;'>#雌激素依赖性乳腺癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98758, encryptionId=316798e58dc, topicName=雌激素依赖性乳腺癌)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Thu Oct 27 09:51:00 CST 2016, time=2016-10-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=95582, encodeId=3a0d9558248, content=了解一下!, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Tue Aug 02 22:16:00 CST 2016, time=2016-08-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1581214, encodeId=90881581214bb, content=<a href='/topic/show?id=4995186984' target=_blank style='color:#2F92EE;'>#ACOG#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1869, encryptionId=4995186984, topicName=ACOG)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=仁心济世, createdTime=Thu Feb 25 15:51:00 CST 2016, time=2016-02-25, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=2030984, encodeId=5e68203098494, content=<a href='/topic/show?id=5df2460e269' target=_blank style='color:#2F92EE;'>#实践指南#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46072, encryptionId=5df2460e269, topicName=实践指南)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=796422, createdName=lvliquan, createdTime=Sun Mar 06 05:51:00 CST 2016, time=2016-03-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1816406, encodeId=458a1816406e8, content=<a href='/topic/show?id=0c649e6170f' target=_blank style='color:#2F92EE;'>#阴道雌激素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97617, encryptionId=0c649e6170f, topicName=阴道雌激素)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3c932500160, createdName=ms7421025882867189, createdTime=Tue Jan 17 05:51:00 CST 2017, time=2017-01-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1991143, encodeId=9d2819911433e, content=<a href='/topic/show?id=316798e58dc' target=_blank style='color:#2F92EE;'>#雌激素依赖性乳腺癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98758, encryptionId=316798e58dc, topicName=雌激素依赖性乳腺癌)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Thu Oct 27 09:51:00 CST 2016, time=2016-10-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=95582, encodeId=3a0d9558248, content=了解一下!, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Tue Aug 02 22:16:00 CST 2016, time=2016-08-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1581214, encodeId=90881581214bb, content=<a href='/topic/show?id=4995186984' target=_blank style='color:#2F92EE;'>#ACOG#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1869, encryptionId=4995186984, topicName=ACOG)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=仁心济世, createdTime=Thu Feb 25 15:51:00 CST 2016, time=2016-02-25, status=1, ipAttribution=)]
    2016-08-02 1dd8c52fm63(暂无匿称)

    了解一下!

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=2030984, encodeId=5e68203098494, content=<a href='/topic/show?id=5df2460e269' target=_blank style='color:#2F92EE;'>#实践指南#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46072, encryptionId=5df2460e269, topicName=实践指南)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=796422, createdName=lvliquan, createdTime=Sun Mar 06 05:51:00 CST 2016, time=2016-03-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1816406, encodeId=458a1816406e8, content=<a href='/topic/show?id=0c649e6170f' target=_blank style='color:#2F92EE;'>#阴道雌激素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97617, encryptionId=0c649e6170f, topicName=阴道雌激素)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3c932500160, createdName=ms7421025882867189, createdTime=Tue Jan 17 05:51:00 CST 2017, time=2017-01-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1991143, encodeId=9d2819911433e, content=<a href='/topic/show?id=316798e58dc' target=_blank style='color:#2F92EE;'>#雌激素依赖性乳腺癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98758, encryptionId=316798e58dc, topicName=雌激素依赖性乳腺癌)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Thu Oct 27 09:51:00 CST 2016, time=2016-10-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=95582, encodeId=3a0d9558248, content=了解一下!, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Tue Aug 02 22:16:00 CST 2016, time=2016-08-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1581214, encodeId=90881581214bb, content=<a href='/topic/show?id=4995186984' target=_blank style='color:#2F92EE;'>#ACOG#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1869, encryptionId=4995186984, topicName=ACOG)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=仁心济世, createdTime=Thu Feb 25 15:51:00 CST 2016, time=2016-02-25, status=1, ipAttribution=)]
    2016-02-25 仁心济世

相关资讯

ACOG:妇产科医生需警惕再加工的一次性医疗器材

    鉴于目前越来越多的医院为了缩减成本而使用再加工的一次性医疗器材,美国妇产科医师协会(ACOG)提醒妇产科医生警惕手术中是否会用到这类再加工的医疗器材,如需使用一定要确保其安全性。     ACOG妇科实践委员会在《妇产科学》(Obstetrics & Gynecology) 10月刊上发布了一份委员会意见:应告知医生其手