JAMA Intern Med:早产增加成年期缺血性心脏病风险

2019-06-05 MedSci MedSci原创

研究认为,早产与成年期缺血性心脏病风险增加相关

研究已证实早产与成年期高血压糖尿病风险增加有关,近日研究人员开展以人群为基础的大型队列中,确定早产是否与成年期缺血性心脏病(IHD)相关。

1973-1994年,2141709瑞典出生的独生子女参与研究,收集年全国住院和门诊诊断的缺血性心脏病数据。

参与者中,1041906(48.6%)为女性,1921人(0.09%)在3090万人年的随访中接受了IHD诊断。出生时的胎龄与成年时的IHD风险呈负相关。30-43岁时,与足月分娩(39-41周)人群相比,极早产(胎龄<37周)和早产(37-38周)人群相关的IHD校正危险比分别为1.53和1.19。早产女性的IHD发生率低于早产男性(15.16 vs 22.00/100 000人-年),调整后的危险进一步增加(1.93 vs 1.37)。

研究认为,早产与成年期缺血性心脏病风险增加相关。

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