J Thromb Haemost:简化的日内瓦评分评估肺栓塞的临床可能性!

2017-07-09 xing.T MedSci原创

由此可见,使用SGS与GS在排除PE的安全性上相似,并与D-二聚体检测相关。

临床预测规则(CPR)评估的检验前概率评估是可疑肺栓塞(PE)患者管理的重要步骤。CPR使用的一个限制是他们的结构性变量和相应的分数很难记住。最近,研究人员已经提出了日内瓦评分的简化版本(即将每一分归因于每个变量),但从未进行过前瞻性验证。近日,血栓和凝血疾病权威杂志Journal of Thrombosis and Haemostasis上发表了一篇研究文章,研究人员旨在前瞻性的验证简化的日内瓦评分(SGS)并与前一版本的日内瓦评分(GS)进行比较。在ADJUST-PE研究中,其主要目的是验证年龄调整的D-二聚体临界值,SGS被前瞻性地用于测定包含1621例研究患者的子样本检验前的可能性。总体而言,有294例(18.1%)患者被确诊为PE。使用SGS,分别有608例(37.5%)、980例(60.5%)和33例(2%)患者被归类为具有低、中、高临床可能性。对应的PE的患病率分别为9.7%、22.4%和45.5%;490例(30.1%)低或中等可能性的患者D-二聚体水平低于500μg/L,653例(41.1%)患者根据年龄调整的临界值D-二聚体检测阴性。使用GS,对应的数值为:491例

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    2018-02-24 changfy
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    2017-07-15 天涯183

    非常好的文章,学习了,很受益

    0

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    2017-07-09 楠博One

    学习谢谢分享

    0

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    2017-07-09 天涯183

    非常好的文章,学习了,很受益

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    2017-07-09 1e0f8808m18(暂无匿称)

    D一二聚体是诊断肺栓塞的重要标志物。

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    2017-07-09 135****7952平儿

    学了。。。。。。。。。。。。

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    2017-07-09 清风拂面

    谢谢分享,学习了

    0

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