Int J Nanomed:重磅!研究表明,维生素D3可以帮助治愈或预防心血管损伤

2018-01-31 白木清水 来宝网

俄亥俄大学科学家进行的一项新研究表明,多一点阳光可能有助于恢复对心血管系统的损害。

俄亥俄大学科学家进行的一项新研究表明,多一点阳光可能有助于恢复对心血管系统的损害。

这项研究表明,当皮肤暴露在阳光下时,身体自然产生的维生素D3——可以显着地恢复由多种疾病引起的心血管系统的损伤,包括高血压糖尿病和动脉粥样硬化。

一般来说,维生素D3与骨骼有关。然而,近年来,在临床环境中,人们认识到许多心脏病发作的患者会缺乏D3。这并不意味着心脏病发作的原因,但它增加了心脏病发作的风险,”Malinski说。“我们使用纳米传感器来了解为什么维生素D3可以有益,尤其是对心血管系统的功能和恢复。”

Malinski的研究小组利用纳米传感器开发了独特的测量方法和测量系统,它的直径比人的头发小1000倍,可以追踪维生素D3对单个内皮细胞的影响,这是心血管系统的重要调节成分。这些研究的一个重要发现是,维生素D3是一氧化氮(NO)的强大刺激因子,一氧化氮是调节血液流动和防止心血管系统血栓形成的主要信号分子。此外,维生素D3可以显着降低心血管系统的氧化应激水平。

最重要的是,这些研究表明,维生素D3的治疗可以显着地恢复由多种疾病引起的心血管系统的损伤,包括高血压、动脉粥样硬化和糖尿病,同时也降低了心脏病发作的风险。

“不是有很多,如果有的话,已知的系统可以用来恢复被损坏的已心血管内皮细胞,而维生素D3能做到这一点,” Malinski说。这是一种非常便宜的修复心血管系统的方法。我们不需要开发一种新药。”

这些研究是在俄亥俄大学进行的,是第一个发现维生素d3触发恢复的分子机制,在心血管疾病中受损的内皮细胞的功能。虽然这些研究使用的是细胞模型的高血压,但维生素D3对功能紊乱的内皮的影响更广泛。内皮功能障碍是几种心血管疾病的共同特征,尤其是与缺血事件有关的疾病。

因此,作者认为维生素D3在恢复心肌内皮功能紊乱后可能具有重要的临床意义,如心肌缺血(中风)、低血容量、血管病变、糖尿病和动脉粥样硬化等。这一建议得到了几项临床研究的有力支持,这些研究表明,维生素D3的剂量高于目前用于治疗骨病的剂量,可能对治疗功能失调的心血管系统非常有益。

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    2018-02-02 xxxx1054
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    2018-02-01 121832a9m88暂无昵称

    学习了

    0

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    2018-01-31 有备才能无患

    俄亥俄大学科学家进行的一项新研究表明.多一点阳光可能有助于恢复对心血管系统的损害.

    0

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    2018-01-31 hhh678

    henhao

    0

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