J Mech Behav Biomed Mater:石墨烯增强45S5或是承重骨植入物的理想材料

2017-11-27 MedSci MedSci原创

45S5Bioglass®(45S5)由于其优异的生物相容性和生物活性,是陶瓷基植骨替代物中使用最广泛的生物材料之一。然而,45S5的断裂韧性和耐磨性有待提高,以提高其在整形外科植入物中的应用。本研究首次使用石墨烯纳米片(GNP)来提高45S5的断裂韧性和耐磨性。通过放电等离子体烧结(SPS)在550℃的相对低的温度下烧结具有四种不同负载量的氧化石墨烯(G O)(即0,0.1,0.5和1重量%)的

45S5Bioglass®(45S5)由于其优异的生物相容性和生物活性,是陶瓷基植骨替代物中使用最广泛的生物材料之一。然而,45S5的断裂韧性和耐磨性有待提高,以提高其在整形外科植入物中的应用。

本研究首次使用石墨烯纳米片(GNP)来提高45S5的断裂韧性和耐磨性。通过放电等离子体烧结(SPS)在550℃的相对低的温度下烧结具有四种不同负载量的氧化石墨烯(G O)(即0,0.1,0.5和1重量%)的复合粉末。结果发现,在45S5粉末中加入0.5wt%GO,烧结球团的断裂韧性提高了130.2%,摩擦系数和比磨损率分别下降了21.3%和62.0%。此外,与在纯45S5相比,在GNP上生长的MG63细胞的生存力一样高。与纯45S5渗滤液相比,用GO含量为1wt%的复合粉末制备的GNP/45S5颗粒制备的培养基能增强MG63细胞的增殖和活力。

因此,本研究结果表明,GNP增强型45S5可用于制造机械强度和生物相容性的承重骨植入物。

原始出处:

Li Z, Khun NW, Tang XZ, Liu E, Khor KA. Mechanical, tribological and biological properties of novel 45S5 Bioglass® composites reinforced with in situ reduced graphene oxide. J Mech Behav Biomed Mater. 2017 Jan;65:77-89. doi: 10.1016/j.jmbbm.2016.08.007. Epub 2016 Aug 6.

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    2018-08-10 sunylz
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    2017-11-29 linagood
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    2017-11-29 jiyangfei
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    2017-11-29 qjddjq
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  8. [GetPortalCommentsPageByObjectIdResponse(id=1947863, encodeId=19cc194e863a1, content=<a href='/topic/show?id=e54d8483db' target=_blank style='color:#2F92EE;'>#HAV#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8483, encryptionId=e54d8483db, topicName=HAV)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3fc52500170, createdName=12498cbcm00(暂无昵称), createdTime=Sun Oct 21 01:48:00 CST 2018, time=2018-10-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1651530, encodeId=8b1e165153063, content=<a href='/topic/show?id=6e78e32573c' target=_blank style='color:#2F92EE;'>#石墨烯#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73257, encryptionId=6e78e32573c, topicName=石墨烯)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8db924213398, createdName=yangjxjc, createdTime=Wed Jun 20 01:48:00 CST 2018, time=2018-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1917804, encodeId=7b15191e80413, content=<a href='/topic/show?id=4f26341994' target=_blank style='color:#2F92EE;'>#Bio#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3419, encryptionId=4f26341994, topicName=Bio)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=12de429, createdName=sunylz, createdTime=Fri Aug 10 19:48:00 CST 2018, time=2018-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1490883, encodeId=5818149088304, content=<a href='/topic/show?id=fb916268636' target=_blank style='color:#2F92EE;'>#植入物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62686, encryptionId=fb916268636, topicName=植入物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=38628846382, createdName=linagood, createdTime=Wed Nov 29 12:48:00 CST 2017, time=2017-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1520426, encodeId=684215204267b, content=<a href='/topic/show?id=7a736264553' target=_blank style='color:#2F92EE;'>#植入#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=19, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62645, encryptionId=7a736264553, topicName=植入)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=832411313664, createdName=jiyangfei, createdTime=Wed Nov 29 12:48:00 CST 2017, time=2017-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1521885, encodeId=b195152188512, content=<a href='/topic/show?id=f83866137f' target=_blank style='color:#2F92EE;'>#EHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6613, encryptionId=f83866137f, topicName=EHA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=937d11405368, createdName=qjddjq, createdTime=Wed Nov 29 12:48:00 CST 2017, time=2017-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1608289, encodeId=7ae416082899d, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=14, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Wed Nov 29 12:48:00 CST 2017, time=2017-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=264873, encodeId=67e62648e39b, content=谢谢分享.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Mon Nov 27 22:37:53 CST 2017, time=2017-11-27, status=1, ipAttribution=)]
    2017-11-27 清风拂面

    谢谢分享.学习了

    0