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Plos one：摄入多不饱和脂肪可延缓糖尿病进展

2016-03-28 Seven L MedSci原创

血糖脂肪糖尿病
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新研究表明，饮食里使用多不饱和脂肪代替饱和脂肪，可减缓前驱糖尿病进展为2型糖尿病的速度。伦敦国王大学糖尿病和营养学部门的Nicola Guess博士说：“研究结果表明，前驱糖尿病患者将受益于增多的多不饱和脂肪的摄入量。”Guess和同事对15名血糖量正常的参与者、14名运动员、23名肥胖人群、10名前驱葡萄糖患者和11名2型糖尿病患者进行了研究，探究饮食中脂肪酸的摄入对空腹血糖和餐后2小时血糖水平


新研究表明，饮食里使用多不饱和脂肪代替饱和脂肪，可减缓前驱糖尿病进展为2型糖尿病的速度。

伦敦国王大学糖尿病和营养学部门的Nicola Guess博士说：“研究结果表明，前驱糖尿病患者将受益于增多的多不饱和脂肪的摄入量。”

Guess和同事对15名血糖量正常的参与者、14名运动员、23名肥胖人群、10名前驱葡萄糖患者和11名2型糖尿病患者进行了研究，探究饮食中脂肪酸的摄入对空腹血糖和餐后2小时血糖水平的影响。研究人员对所有参与者进行了口服葡萄糖耐量试验和高胰岛素-正葡萄糖钳夹术。

研究数据显示，空腹血糖与饱和脂肪(P = .004)和反式脂肪(P = .045)间具有正相关，而抑制肝葡萄糖生产的百分比与饱和脂肪(P = .032) 和反式脂肪 (P = .06)间具有负相关。研究者没有发现空腹血糖或抑制肝葡萄糖生产的百分比与多不饱和脂肪间的关系。

此外，餐后2小时血糖与饱和脂肪(P = .005)和反式脂肪(P = .001)间具有正相关，与多不饱和脂肪呈负相关(P = .021)；高胰岛素-正葡萄糖钳夹术中葡萄糖的消失率与饱和脂肪(P = .001) 和反式脂肪 (P = .021)间具有负相关，与多不饱和脂肪呈正相关(P = .081)。

作者写道：“研究结果表明，饮食中饱和脂肪的摄入会导致更高的空腹血糖和餐后2小时血糖，饮食中反式脂肪和多不饱和脂肪对餐后2小时血糖的调节具有相反的作用。因此对空腹血糖和糖耐量受损的人群，通过生活方式的改变，或许可以延缓疾病的进展。”

原始出处：

Guess N, et al. Dietary Fatty Acids Differentially Associate with Fasting Versus 2-Hour Glucose Homeostasis: Implications for The Management of Subtypes of Prediabetes.PLoS One. 2016;doi:10.1371/journal.pone.0150148.

Polyunsaturated fat may slow type 2 diabetes progression.Healio.March 23, 2016

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    2016-08-20 119337457

    #Plos one#

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=1789788, encodeId=0ccf1e897885b, content=<a href='/topic/show?id=6e4814388e2' target=_blank style='color:#2F92EE;'>#Plos one#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14388, encryptionId=6e4814388e2, topicName=Plos one)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fda6311, createdName=119337457, createdTime=Sat Aug 20 19:00:00 CST 2016, time=2016-08-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1579955, encodeId=0bfd15e9955d5, content=<a href='/topic/show?id=65f0101268d6' target=_blank style='color:#2F92EE;'>#饱和脂肪#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101268, encryptionId=65f0101268d6, topicName=饱和脂肪)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b0db16571375, createdName=斯嘉莉, createdTime=Wed Mar 30 05:00:00 CST 2016, time=2016-03-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=74419, encodeId=df6be441933, content=补鱼肝油, beContent=null, objectType=article, channel=null, level=null, likeNumber=117, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuHfSLw3PzIKiaSnTBUuAtRkrrxWpibukl35iciaGtBq4LYQv4ian1tPC3IdmzWI2dZ3cDC8wUg5CnBxlJ/0, createdBy=33a51675735, createdName=jiangxianchen, createdTime=Tue Mar 29 09:34:00 CST 2016, time=2016-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=74392, encodeId=2618e43926e, content=的确这样, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7cde98330, createdName=milkshark, createdTime=Tue Mar 29 06:52:00 CST 2016, time=2016-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=74393, encodeId=ef2fe439364, content=值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7cde98330, createdName=milkshark, createdTime=Tue Mar 29 06:52:00 CST 2016, time=2016-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=74271, encodeId=14e5e427129, content=给家人买鱼油要, beContent=null, objectType=article, channel=null, level=null, likeNumber=160, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0a6a1604604, createdName=Gsurgeon, createdTime=Mon Mar 28 23:37:00 CST 2016, time=2016-03-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=74232, encodeId=0cc1e423260, content=这个好像确实有效, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e4371683642, createdName=文医生, createdTime=Mon Mar 28 19:04:00 CST 2016, time=2016-03-28, status=1, ipAttribution=)]
    2016-03-30 斯嘉莉

    #饱和脂肪#

    0

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    2016-03-29 jiangxianchen

    补鱼肝油

    0

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    2016-03-29 milkshark

    的确这样

    0

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    2016-03-29 milkshark

    值得学习

    0

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    2016-03-28 Gsurgeon

    给家人买鱼油要

    0

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    2016-03-28 文医生

    这个好像确实有效

    0

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