Heart:先心病患者有较高的感染性心内膜炎发生率和死亡率

2018-01-04 MedSci MedSci原创

感染性心内膜炎(IE)有较高的发生率和死亡率,成年先天性心脏病(ACHD)患者患IE的风险更高,本研究的目的旨在评估ACHD患者发生感染性心内膜炎的发生率、死亡率和预测结局的相关因素。本研究纳入了1999-2013年诊断为感染性心内膜炎的成年先心病患者,主要终点事件是心内膜炎相关死亡率。最终,共有144名患者发生了164例感染性心内膜炎(男性有102名,占70.8%),平均年龄为32.3±22.7

感染性心内膜炎(IE)有较高的发生率和死亡率,成年先天性心脏病(ACHD)患者患IE的风险更高,本研究的目的旨在评估ACHD患者发生感染性心内膜炎的发生率、死亡率和预测结局的相关因素。

本研究纳入了1999-2013年诊断为感染性心内膜炎的成年先心病患者,主要终点事件是心内膜炎相关死亡率。最终,共有144名患者发生了164例感染性心内膜炎(男性有102名,占70.8%),平均年龄为32.3±22.7岁。其中有37起感染性心内膜炎是二次甚至是多次感染,有67例IE(37.2%)接受了外科手术治疗。经过平均6.7年时间的随访,有28名(19.4%)患者死亡,其中有10名死于IE(6.9%)。回归分析结果显示,脓肿(OR: 7.23; 95% CI 1.81-28.94, p<0.01)和年龄(OR: 1.05; 95% CI 1.01-1.10, p=0.03)是预测IE相关死亡的因素。

研究结果显示,在成年先心病患者中,感染性心内膜炎的发生率和死亡率较高,脓肿和年龄是预测IE相关死亡的因素。

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    2018-01-06 ssnine
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    2018-01-06 zhaojie88
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    2018-01-06 slcumt
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    2018-01-04 沙漠浪人

    在成年先心病患者中.感染性心内膜炎的发生率和死亡率较高.脓肿和年龄是预测IE相关死亡的因素.

    0

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    2018-01-04 happsf

    学习

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