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罗氏肺癌联合化疗延长PFS

2017-12-08 MedSci MedSci原创

肺癌联合化疗
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罗氏(Roche)的Tecentriq(atezolizumab)和Avastin(bevacizumab)+化疗药(卡铂和紫杉醇)的组合表明，在未经治疗的非鳞状非小细胞肺癌(NSCLC)患者中，患者的无进展生存率为37%。是Avastin +化疗药(18%) PFS的两倍，具有里程碑式的意义。III期IMpower150研究还显示，使用Tecentriq和Avastin联合化疗的患者中，与Ava

罗氏(Roche)的Tecentriq(atezolizumab)和Avastin(bevacizumab)+化疗药(卡铂和紫杉醇)的组合表明，在未经治疗的非鳞状非小细胞肺癌(NSCLC)患者中，患者的无进展生存率为37%。是Avastin +化疗药(18%) PFS的两倍，具有里程碑式的意义。III期IMpower150研究还显示，使用Tecentriq和Avastin联合化疗的患者中，与Avastin联合化疗相比，研究次要终点肿瘤缩小的比例更高（64％比48％）。"这是第一个积极的III期联合试验，它显示了癌症免疫疗法降低了病情恶化的风险，这是一种早期治疗，广泛用于非鳞状细胞肺癌患者。" 罗氏首席医疗官、全球产品开发主管桑德拉霍宁(Sandra Horning)表示。"IMpower150的研究代表了肺癌治疗的一个重要进展，我们将把这些结果提交给世界各地的监管机构，以潜在地为患有这种疾病的人提供新的治疗标准。"原文出处：http：//www.pharmatimes.com/news/roche_lung_cancer_combo_doubles_pfs_rates_1213861此

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  1. [GetPortalCommentsPageByObjectIdResponse(id=288668, encodeId=a0b428866893, content=学到了知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=361b2226758, createdName=紫萱木木, createdTime=Sat Feb 17 11:02:40 CST 2018, time=2018-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=268453, encodeId=7fb026845369, content=不错的文章值得推荐, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Sun Dec 10 23:41:16 CST 2017, time=2017-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1411718, encodeId=267c1411e18d4, content=<a href='/topic/show?id=a53e806837f' target=_blank style='color:#2F92EE;'>#联合化疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80683, encryptionId=a53e806837f, topicName=联合化疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ebf32807001, createdName=oliver170, createdTime=Sun Dec 10 11:13:00 CST 2017, time=2017-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1448649, encodeId=ca921448649a5, content=<a href='/topic/show?id=aaf21412e7e' target=_blank style='color:#2F92EE;'>#PFS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14127, encryptionId=aaf21412e7e, topicName=PFS)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=47f75418389, createdName=jeanqiuqiu, createdTime=Sun Dec 10 11:13:00 CST 2017, time=2017-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=268057, encodeId=db3b26805e20, content=学习一下知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160718/IMG578C993D395567540.jpg, createdBy=59b81918946, createdName=flysky120, createdTime=Sat Dec 09 09:12:02 CST 2017, time=2017-12-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=267933, encodeId=5ae426e9338f, content=学习一下谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLGSUSR8zwnWWLT4FMl5XH8S58HuZslVkLsAPbXDXaliagK7TOxQfmngKibG1yrDonepCLDkcxGk8hS/0, createdBy=b8282062892, createdName=changjiu, createdTime=Fri Dec 08 23:46:45 CST 2017, time=2017-12-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=267904, encodeId=bad026e9045f, content=陈学冬改变 v 大的风格, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/PiajxSqBRaEKXpC8j9TaoCpG4yIB3skibUZ0ricmVQ6KKIVpqYQxINrmlibsPZSia7GOUupzuINf8UITMib8awsjjkPw/0, createdBy=abbf1713451, createdName=zt123, createdTime=Fri Dec 08 21:51:04 CST 2017, time=2017-12-08, status=1, ipAttribution=)]
    2018-02-17 紫萱木木

    学到了知识

    0

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    2017-12-10 1e1b8538m79(暂无匿称)

    不错的文章值得推荐

    0

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    2017-12-10 oliver170

    #联合化疗#

    0

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    2017-12-10 jeanqiuqiu

    #PFS#

    0

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    2017-12-09 flysky120

    学习一下知识了

    0

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    2017-12-08 changjiu

    学习一下谢谢

    0

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    2017-12-08 zt123

    陈学冬改变 v 大的风格

    0