Radiology:计算机辅助CT测量亚实性结节实性成分评估预后的价值

2018-04-19 shaosai MedSci原创

本研究旨在验证亚实性非小细胞肺癌患者术后情况与多螺旋CT图像3D容积软件中所测实性成分大小的关系,并将结果发表在Radiology上。

本研究旨在验证亚实性非小细胞肺癌患者术后情况与多螺旋CT图像3D容积软件中所测实性成分大小的关系,并将结果发表在Radiology上。

本研究共纳入了96例术前行多螺旋CT发现亚实性非小细胞肺癌的患者(男性47例,女性49例;平均年龄±标准差为66岁±8)。由两名放射科医生测量每个结节轴位相2D最大大小(2D MSSA)、在重建图像上3D实性成分大小(3D MSSMPR)和每个结节中CT值超高0HU的实性体积(3D SV 0HU)。利用Cox比例风险模型评价术后复发和临床病史、病理特点、2D MSSA、 3D MSSMPR、3D SV 0HU 。

结果为,对于预测术后复发,2D MSSA、 3D MSSMPR、3D SV 0HU 的曲线下面积分别为0.796 (95% CI: 0.692, 0.900)/0.776 (95%CI: 0.667, 0.886)、0.835 (95%CI: 0.749, 0.922) 。3D SV 0HU 预测肿瘤复发的最佳截断值为0.54 cm 3,敏感性、特异性分别为0.933 (95% CI: 0.679, 0.998)、0.716 (95% CI: 0.605, 0.811)。无病生存期的预测因子权重3D SV 0HU 要不低于0.54 cm 3 (HR为6.61; P = .001) ,其次为淋巴结或血管受侵犯(HR, 2.96; P = .040)。

本研究表明,测量3D SV 0HU能够预测亚实性肺癌术后情况要比2D MSSA、3D MSSMPR更为准确。

原始出处:

Kamiya S, Iwano S, Umakoshi H. et al.Computer-aided Volumetry of Part-Solid Lung Cancers by Using CT: Solid Component Size Predicts Prognosis.Radiology.DOI: 10.1148/radiol.2018172319

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    2019-03-06 bioon14
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    2018-05-29 衣觉

    不错的思路-学习

    0

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    2018-04-21 秀红

    学习了

    0

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    2018-04-20 121832a9m88暂无昵称

    学习了

    0

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    2018-04-20 121832a9m88暂无昵称

    学习了

    0

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    2018-04-19 龙胆草

    学习谢谢分享

    0

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    2018-04-19 swfzhanggui

    非常好.谢谢分享

    0

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    2018-04-19 wzb521zf

    一起学习学习

    0

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    2018-04-19 1209e435m98(暂无昵称)

    学习了.谢谢分享

    0

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    2018-04-19 yjs木玉

    学习学习再学习

    0

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